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Cpr65Au Cuticular protein 65Au [ Drosophila melanogaster (fruit fly) ]

Gene ID: 59158, updated on 9-Dec-2024

Summary

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Official Symbol
Cpr65Auprovided by FlyBase
Official Full Name
Cuticular protein 65Auprovided by FlyBase
Primary source
FLYBASE:FBgn0042119
Locus tag
Dmel_CG18778
See related
AllianceGenome:FB:FBgn0042119
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:GH21145; CG18778; DmelCpr65Au; Dmel\CG18778
Summary
Predicted to be a structural constituent of chitin-based larval cuticle. Predicted to be involved in chitin-based cuticle development. Predicted to be active in chitin-based extracellular matrix. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See Cpr65Au in Genome Data Viewer
Location:
65A6-65A6; 3-16 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (6131242..6132109, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (6124342..6125209, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene lethal (3) malignant blood neoplasm Neighboring gene antisense RNA:CR46005 Neighboring gene Larval cuticle protein Neighboring gene Lcp65Ag2 Neighboring gene Lcp65Ag1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Population Genomics of sub-saharan Drosophila melanogaster: African diversity and non-African admixture. Pool JE, et al. PLoS Genet, 2012. PMID 23284287, Free PMC Article
  2. Drosophila PDGF/VEGF signaling from muscles to hepatocyte-like cells protects against obesity. Ghosh AC, et al. Elife, 2020 Oct 27. PMID 33107824, Free PMC Article
  3. Elucidating the "Gravome": Quantitative Proteomic Profiling of the Response to Chronic Hypergravity in Drosophila. Hosamani R, et al. J Proteome Res, 2016 Dec 2. PMID 27648494
  4. The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. Bellen HJ, et al. Genetics, 2004 Jun. PMID 15238527, Free PMC Article
  5. Mitf is a master regulator of the v-ATPase, forming a control module for cellular homeostasis with v-ATPase and TORC1. Zhang T, et al. J Cell Sci, 2015 Aug 1. PMID 26092939, Free PMC Article

See all (33) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables structural constituent of chitin-based larval cuticle IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of chitin-based larval cuticle ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in chitin-based cuticle development ISM
Inferred from Sequence Model
more info
 PubMed 
Component Evidence Code Pubs
is_active_in chitin-based extracellular matrix IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in chitin-based extracellular matrix ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
cuticular protein 65Au
Names
CG18778-PA
CG18778-PB
Cpr65Au-PA
Cpr65Au-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    6131242..6132109 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001300024.1 → NP_001286953.1  cuticular protein 65Au, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001286953.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9I7Q5
    Conserved Domains (1) summary
    pfam00379
    Location:42 → 98
    Chitin_bind_4; Insect cuticle protein

  2. NM_144404.2 → NP_652661.1  cuticular protein 65Au, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_652661.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9I7Q5
    Related
    FBpp0076768
    Conserved Domains (1) summary
    pfam00379
    Location:42 → 98
    Chitin_bind_4; Insect cuticle protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9I7Q5 Q9I7Q5

Gene LinkOut

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