mespaa - mesoderm posterior aa
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including blood vessel endothelial cell fate specification; gastrulation; and regionalization. Predicted to be active in nucleus. Is expressed in several structures, including blastoderm; hypoblast; margin; paraxial mesoderm; and presumptive paraxial mesoderm. Human ortholog(s) of this gene implicated in spondylocostal dysostosis 2. Orthologous to human MESP2 (mesoderm posterior bHLH transcription factor 2). [provided by Alliance of Genome Resources, Dec 2024]
NCBI Orthologs
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Protein alignment
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