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DEFB119 defensin beta 119 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 574286, updated on 3-Dec-2024

Summary

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Official Symbol
DEFB119provided by VGNC
Official Full Name
defensin beta 119provided by VGNC
Primary source
VGNC:VGNC:82134
Locus tag
EGK_02544
See related
Ensembl:ENSMMUG00000008796
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as
DEFB120
Orthologs
human mouse all
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Genomic context

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See DEFB119 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
3
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (66631622..66644823, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (32679569..32692761)

Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene defensin beta 118 Neighboring gene small nucleolar RNA SNORA40 Neighboring gene defensin beta 121 Neighboring gene beta defensin 122

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification, characterization, and evolution of a primate beta-defensin gene cluster. Radhakrishnan Y, et al. Genes Immun, 2005 May. PMID 15772680, Free PMC Article
  2. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  3. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables lipopolysaccharide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in antifungal innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response to Gram-negative bacterium IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response to Gram-positive bacterium IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
beta-defensin 119
Names
beta-defensin 120
defensin, beta 120

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001032908.2 → NP_001028080.1  beta-defensin 119 isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    QNVO02000030
    UniProtKB/Swiss-Prot
    Q5J601, Q5J602
    UniProtKB/TrEMBL
    I0FIH0
    Related
    ENSMMUP00000011534.1, ENSMMUT00000012296.3
    Conserved Domains (1) summary
    pfam14862
    Location:17 → 52
    Defensin_big; Big defensin

  2. NM_001032909.2 → NP_001028081.1  beta-defensin 119 isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    QNVO02000030
    UniProtKB/TrEMBL
    G7N561

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041763.1 Reference Mmul_10 Primary Assembly

    Range
    66631622..66644823 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015149288.2 → XP_015004774.1  beta-defensin 119 isoform X1

    Related
    ENSMMUP00000011536.4, ENSMMUT00000012298.4
    Conserved Domains (1) summary
    pfam13841
    Location:22 → 50
    Defensin_beta_2; Beta defensin
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5J602.1 GenPept UniProtKB/Swiss-Prot:Q5J602

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.