GHRL ghrelin and obestatin prepropeptide [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: GHRLprovided by VGNC
Official Full Name: ghrelin and obestatin prepropeptideprovided by VGNC
Primary source: VGNC:VGNC:72963
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	2	NC_041755.1 (141695163..141699444, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	2	NC_027894.1 (56021018..56028066)

Chromosome 2 - NC_041755.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

increased caloric intake by subordinates may, in part, be explained by a greater sensitivity to postprandial increases in ghrelin and that CRH receptor antagonism leading to a decrease in cortisol has mixed effects on food choice depending on stress
Title: Increased ghrelin sensitivity and calorie consumption in subordinate monkeys is affected by short-term astressin B administration.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ghrelin receptor binding	IEA Inferred from Electronic Annotation more info	PubMed
enables growth hormone-releasing hormone activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in gastric acid secretion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in negative regulation of inflammatory response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of growth hormone secretion	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of response to food	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: appetite-regulating hormone

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001032903.1 → NP_001028075.1 appetite-regulating hormone precursor

See identical proteins and their annotated locations for NP_001028075.1

Status: PROVISIONAL

Source sequence(s)

AY371699

UniProtKB/TrEMBL

Q6UDE7

Conserved Domains (2) summary

pfam04643
Location:57 → 115

Motilin_assoc; Motilin/ghrelin-associated peptide

pfam04644
Location:25 → 51

Motilin_ghrelin; Motilin/ghrelin