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MNP2 alpha-defensin 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 574197, updated on 9-Nov-2023

Summary

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Gene symbol
MNP2
Gene description
alpha-defensin 2
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as
RMAD-4; RMAD-6
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Genomic context

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See MNP2 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
3
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 8 NC_041761.1 (7799298..7807253, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 8 NC_027900.1 (7209027..7216988, complement)

Chromosome 8 - NC_041761.1Genomic Context describing neighboring genes Neighboring gene defensin alpha 1B Neighboring gene uncharacterized LOC106999660 Neighboring gene defensin, alpha 4, corticostatin Neighboring gene alpha-defensin 3 precursor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Isolation, characterization, cDNA cloning, and antimicrobial properties of two distinct subfamilies of alpha-defensins from rhesus macaque leukocytes. Tang YQ, et al. Infect Immun, 1999 Nov. PMID 10531277, Free PMC Article
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in antibacterial humoral response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in antimicrobial humoral immune response mediated by antimicrobial peptide IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to lipopolysaccharide IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response to Gram-negative bacterium IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response to Gram-positive bacterium IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in disruption of plasma membrane integrity in another organism IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response in mucosa IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
neutrophil defensin 6
Names
Neutrophil defensin 4
Neutrophil defensin 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001032863.3 → NP_001028035.1  neutrophil defensin 6 precursor

    See identical proteins and their annotated locations for NP_001028035.1

    Status: VALIDATED

    Source sequence(s)
    QNVO02000449
    UniProtKB/Swiss-Prot
    P82319
    UniProtKB/TrEMBL
    Q9TTZ8
    Conserved Domains (2) summary
    pfam00323
    Location:76 → 93
    Defensin_1; Mammalian defensin
    pfam00879
    Location:1 → 49
    Defensin_propep; Defensin propeptide

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041761.1 Reference Mmul_10 Primary Assembly

    Range
    7799298..7807253 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P82319.1 GenPept UniProtKB/Swiss-Prot:P82319
P82320.1 GenPept UniProtKB/Swiss-Prot:P82320

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials