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SCN9A sodium voltage-gated channel alpha subunit 9 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 574119, updated on 17-Aug-2024

Summary

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Official Symbol
SCN9Aprovided by VGNC
Official Full Name
sodium voltage-gated channel alpha subunit 9provided by VGNC
Primary source
VGNC:VGNC:76990
See related
Ensembl:ENSMMUG00000018510
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as
ENACH
Orthologs
human mouse all
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Genomic context

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See SCN9A in Genome Data Viewer
Location:
chromosome: 12
Exon count:
28
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 12 NC_041765.1 (53352971..53536263, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 12 NC_027904.1 (53132697..53313153, complement)

Chromosome 12 - NC_041765.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114671340 Neighboring gene tetratricopeptide repeat domain 21B Neighboring gene sodium voltage-gated channel alpha subunit 1 Neighboring gene uncharacterized LOC106992602 Neighboring gene L-lactate dehydrogenase B chain pseudogene Neighboring gene small nucleolar RNA U13 Neighboring gene sodium voltage-gated channel alpha subunit 7 Neighboring gene uncharacterized LOC106992604 Neighboring gene uncharacterized LOC114671342

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of an ovarian voltage-activated Na+-channel type: hints to involvement in luteolysis. Bulling A, et al. Mol Endocrinol, 2000 Jul. PMID 10894155
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables voltage-gated sodium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in membrane depolarization during action potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuronal action potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sodium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of voltage-gated sodium channel complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sodium channel protein type 9 subunit alpha
Names
sodium channel, voltage-gated, type IX, alpha subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041765.1 Reference Mmul_10 Primary Assembly

    Range
    53352971..53536263 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028830806.1 → XP_028686639.1  sodium channel protein type 9 subunit alpha isoform X2

    UniProtKB/TrEMBL
    F7A8X1, G7N879
    Related
    ENSMMUP00000024352.4, ENSMMUT00000026025.4
    Conserved Domains (5) summary
    cd13433
    Location:1447 → 1499
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:1180 → 1455
    Ion_trans; Ion transport protein
    pfam06512
    Location:971 → 1176
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:488 → 673
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:1763 → 1826
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated

  2. XM_028830807.1 → XP_028686640.1  sodium channel protein type 9 subunit alpha isoform X3

    UniProtKB/TrEMBL
    G7N879
    Related
    ENSMMUP00000024354.4, ENSMMUT00000026027.4
    Conserved Domains (5) summary
    cd13433
    Location:1364 → 1416
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:1420 → 1676
    Ion_trans; Ion transport protein
    pfam06512
    Location:982 → 1187
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:488 → 684
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:1680 → 1743
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated

  3. XM_015110280.2 → XP_014965766.2  sodium channel protein type 9 subunit alpha isoform X1

    UniProtKB/TrEMBL
    G7N879
    Conserved Domains (5) summary
    cd13433
    Location:1458 → 1510
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:1191 → 1466
    Ion_trans; Ion transport protein
    pfam06512
    Location:982 → 1187
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:488 → 684
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:1774 → 1837
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated

  4. XM_028830805.1 → XP_028686638.1  sodium channel protein type 9 subunit alpha isoform X1

    UniProtKB/TrEMBL
    G7N879
    Related
    ENSMMUP00000051886.2, ENSMMUT00000076319.2
    Conserved Domains (5) summary
    cd13433
    Location:1458 → 1510
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:1191 → 1466
    Ion_trans; Ion transport protein
    pfam06512
    Location:982 → 1187
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:488 → 684
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:1774 → 1837
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
Nucleotide Protein
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