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CTSK cathepsin K [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 574112, updated on 17-Aug-2024

Summary

Official Symbol
CTSKprovided by VGNC
Official Full Name
cathepsin Kprovided by VGNC
Primary source
VGNC:VGNC:71559
Locus tag
EGK_01237
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
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Genomic context

See CTSK in Genome Data Viewer
Location:
chromosome: 1
Exon count:
8
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (100322705..100335845)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (125257065..125270204, complement)

Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene cytochrome c-like Neighboring gene aryl hydrocarbon receptor nuclear translocator Neighboring gene U6 spliceosomal RNA Neighboring gene cathepsin S Neighboring gene HORMA domain containing 1 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in immune response IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in proteolysis involved in protein catabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
cathepsin K
Names
cathepsin K preproprotein
NP_001027984.1
XP_015005928.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001032812.2NP_001027984.1  cathepsin K precursor

    See identical proteins and their annotated locations for NP_001027984.1

    Status: PROVISIONAL

    Source sequence(s)
    AF124092
    UniProtKB/Swiss-Prot
    P61277
    UniProtKB/TrEMBL
    A0A8J8YGW4, G7MDI3, H9FQF5
    Conserved Domains (2) summary
    smart00848
    Location:2685
    Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
    cd02248
    Location:116327
    Peptidase_C1A; Peptidase C1A subfamily (MEROPS database nomenclature); composed of cysteine peptidases (CPs) similar to papain, including the mammalian CPs (cathepsins B, C, F, H, L, K, O, S, V, X and W). Papain is an endopeptidase with specific substrate preferences, ...

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041754.1 Reference Mmul_10 Primary Assembly

    Range
    100322705..100335845
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015150442.2XP_015005928.1  cathepsin K isoform X1

    Conserved Domains (2) summary
    smart00848
    Location:45104
    Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
    pfam00112
    Location:134346
    Peptidase_C1; Papain family cysteine protease