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inaF-C inaF-C [ Drosophila melanogaster (fruit fly) ]

Gene ID: 5740497, updated on 9-Dec-2024

Summary

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Official Symbol
inaF-Cprovided by FlyBase
Official Full Name
inaF-Cprovided by FlyBase
Primary source
FLYBASE:FBgn0085350
Locus tag
Dmel_CG34321
See related
AllianceGenome:FB:FBgn0085350
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG34321; Dmel\CG34321; inaF; InaF; INAF; INAF-C
Summary
Enables calcium channel regulator activity. Involved in response to light stimulus. Located in rhabdomere. Is expressed in adult head. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

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See inaF-C in Genome Data Viewer
Location:
10D8-10E1; 1-36 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (11726390..11731765, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (11620423..11625798, complement)

Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene pretaporter Neighboring gene Transport and Golgi organization 10 Neighboring gene uncharacterized protein Neighboring gene inaF-D Neighboring gene inaF-B Neighboring gene inaF-A Neighboring gene pseudo Neighboring gene miniature Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Drosophila TRP channels require a protein with a distinctive motif encoded by the inaF locus. Cheng Y, et al. Proc Natl Acad Sci U S A, 2007 Nov 6. PMID 17968007, Free PMC Article
  2. INAF, a protein required for transient receptor potential Ca(2+) channel function. Li C, et al. Proc Natl Acad Sci U S A, 1999 Nov 9. PMID 10557345, Free PMC Article
  3. Distinct TRP channels are required for warm and cool avoidance in Drosophila melanogaster. Rosenzweig M, et al. Proc Natl Acad Sci U S A, 2008 Sep 23. PMID 18787131, Free PMC Article
  4. Nascent-Seq analysis of Drosophila cycling gene expression. Rodriguez J, et al. Proc Natl Acad Sci U S A, 2013 Jan 22. PMID 23297234, Free PMC Article
  5. Subcellular translocation of the eGFP-tagged TRPL channel in Drosophila photoreceptors requires activation of the phototransduction cascade. Meyer NE, et al. J Cell Sci, 2006 Jun 15. PMID 16735439, Free PMC Article

See all (32) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A Family of Auxiliary Subunits of the TRP Cation Channel Encoded by the Complex inaF Locus.
    Title: A Family of Auxiliary Subunits of the TRP Cation Channel Encoded by the Complex inaF Locus.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables calcium channel regulator activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of membrane potential ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in response to light stimulus IGI
Inferred from Genetic Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in rhabdomere IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
inaF-C
Names
CG34321-PA
inaF-C-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_004354.4 Reference assembly

    Range
    11726390..11731765 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001103489.2 → NP_001096959.1  inaF-C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001096959.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q6IIF2
    Conserved Domains (1) summary
    pfam15018
    Location:92 → 126
    InaF-motif; TRP-interacting helix
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6IIF2 Q6IIF2

Gene LinkOut

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