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tbrg1 transforming growth factor beta regulator 1 [ Danio rerio (zebrafish) ]

Gene ID: 573117, updated on 4-Jan-2025

Summary

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Official Symbol
tbrg1provided by ZNC
Official Full Name
transforming growth factor beta regulator 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-080220-62
See related
Ensembl:ENSDARG00000074996 AllianceGenome:ZFIN:ZDB-GENE-080220-62
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:171428
Summary
Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleus. Orthologous to human TBRG1 (transforming growth factor beta regulator 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
human mouse all
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Genomic context

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See tbrg1 in Genome Data Viewer
Location:
chromosome: 18
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (35228872..35254027)
105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (35254269..35276576)

Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene si:ch211-195m9.3 Neighboring gene cilia and flagella associated protein 45 Neighboring gene protein jagged-1b Neighboring gene uncharacterized LOC137488314 Neighboring gene small nuclear ribonucleoprotein polypeptide A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. CRISPR gRNA phenotypic screening in zebrafish reveals pro-regenerative genes in spinal cord injury. Keatinge M, et al. PLoS Genet, 2021 Apr. PMID 33914736, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
transforming growth factor beta regulator 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001114446.1 → NP_001107918.2  transforming growth factor beta regulator 1

    Status: PROVISIONAL

    Source sequence(s)
    BC155063
    UniProtKB/TrEMBL
    A0A8M1NHI5, A9JST2
    Related
    ENSDARP00000105690.1, ENSDART00000129624.3
    Conserved Domains (3) summary
    pfam05066
    Location:52 → 118
    HARE-HTH; HB1, ASXL, restriction endonuclease HTH domain
    pfam05964
    Location:330 → 379
    FYRN; F/Y-rich N-terminus
    pfam05965
    Location:385 → 460
    FYRC; F/Y rich C-terminus

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007129.7 Reference GRCz11 Primary Assembly

    Range
    35228872..35254027
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021467700.2 → XP_021323375.1  transforming growth factor beta regulator 1 isoform X1

    UniProtKB/TrEMBL
    A0A8M9PQD4, A9JST2
    Conserved Domains (3) summary
    pfam05066
    Location:52 → 103
    HARE-HTH; HB1, ASXL, restriction endonuclease HTH domain
    pfam05964
    Location:308 → 358
    FYRN; F/Y-rich N-terminus
    pfam05965
    Location:364 → 445
    FYRC; F/Y rich C-terminus

  2. XM_009293772.4 → XP_009292047.1  transforming growth factor beta regulator 1 isoform X2

    UniProtKB/TrEMBL
    A0A8M3AJR4, A9JST2
    Conserved Domains (2) summary
    pfam05964
    Location:236 → 285
    FYRN; F/Y-rich N-terminus
    pfam05965
    Location:291 → 366
    FYRC; F/Y rich C-terminus

RNA

  1. XR_011007164.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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