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hnrnpl2 heterogeneous nuclear ribonucleoprotein L2 [ Danio rerio (zebrafish) ]

Gene ID: 573096, updated on 4-Jan-2025

Summary

Official Symbol
hnrnpl2provided by ZNC
Official Full Name
heterogeneous nuclear ribonucleoprotein L2provided by ZNC
Primary source
ZFIN:ZDB-GENE-040426-2707
See related
Ensembl:ENSDARG00000059303 AllianceGenome:ZFIN:ZDB-GENE-040426-2707
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
hnrpl; hnrnpl; fb53f10; fp61c04; zgc:66175; wu:fb53f10; wu:fp61c04
Summary
Predicted to enable mRNA binding activity. Acts upstream of or within regulation of skeletal muscle fiber development. Predicted to be part of ribonucleoprotein complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in hepatocellular carcinoma; lung cancer; and systemic scleroderma. Orthologous to human HNRNPL (heterogeneous nuclear ribonucleoprotein L). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See hnrnpl2 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (5784207..5799183, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (5796545..5811390, complement)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene phosphorylase kinase, gamma 1a (muscle) Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 2 Neighboring gene retinol binding protein 2a, cellular Neighboring gene bromodomain and WD repeat domain containing 1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Clone Names

  • MGC66175, MGC174516

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within mRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of RNA splicing IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within regulation of skeletal muscle fiber development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
heterogeneous nuclear ribonucleoprotein L2
Names
heterogeneous nuclear ribonucleoprotein L

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001423736.1NP_001410665.1  heterogeneous nuclear ribonucleoprotein L2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    BX088654
    UniProtKB/TrEMBL
    A0A8M2BHI2, A8KC22, Q7SYM9
    Related
    ENSDARP00000115723.1, ENSDART00000142334.3
  2. NM_213383.2NP_998548.2  heterogeneous nuclear ribonucleoprotein L2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    BX088654
    UniProtKB/TrEMBL
    A0A0R4IVC0, A0A8M2BGY1, Q7SYM9
    Related
    ENSDARP00000139075.1, ENSDART00000171528.2

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    5784207..5799183 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394932.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    87359..102335 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)