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rbm4.1 RNA binding motif protein 4.1 [ Danio rerio (zebrafish) ]

Gene ID: 573001, updated on 4-Jan-2025

Summary

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Official Symbol
rbm4.1provided by ZNC
Official Full Name
RNA binding motif protein 4.1provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-3902
See related
Ensembl:ENSDARG00000036386 AllianceGenome:ZFIN:ZDB-GENE-030131-3902
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
rbm4; rna-bp4; zgc:56302; wu:fc31f07; wu:fc57h11
Summary
Predicted to enable RNA binding activity. Predicted to be located in nucleus. Predicted to be active in nuclear speck. Orthologous to human RBM4B (RNA binding motif protein 4B). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See rbm4.1 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (22801468..22806803)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (22530174..22535646)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene RNA binding motif protein 4.3 Neighboring gene RNA binding motif protein 4.2 Neighboring gene splicing factor 1 Neighboring gene phosphorylase, glycogen, muscle b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Phylogenetic and molecular characterization of the splicing factor RBM4. Lu CC, et al. PLoS One, 2013. PMID 23527094, Free PMC Article
  2. Analysis of the zebrafish proteome during embryonic development. Lucitt MB, et al. Mol Cell Proteomics, 2008 May. PMID 18212345, Free PMC Article
  3. Identification of zygotic genes expressed at the midblastula transition in zebrafish. O'Boyle S, et al. Biochem Biophys Res Commun, 2007 Jun 29. PMID 17490614
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nuclear speck IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
RNA-binding protein 4.1
Names
RNA binding motif protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199705.1 → NP_955999.1  RNA-binding protein 4.1

    See identical proteins and their annotated locations for NP_955999.1

    Status: PROVISIONAL

    Source sequence(s)
    BC046057
    UniProtKB/Swiss-Prot
    Q6IQ97
    Related
    ENSDARP00000052861.6, ENSDART00000052862.7
    Conserved Domains (3) summary
    smart00343
    Location:161 → 176
    ZnF_C2HC; zinc finger
    cd12606
    Location:2 → 68
    RRM1_RBM4; RNA recognition motif 1 in vertebrate RNA-binding protein 4 (RBM4)
    cd12607
    Location:78 → 144
    RRM2_RBM4; RNA recognition motif 2 in vertebrate RNA-binding protein 4 (RBM4)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    22801468..22806803
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068222371.1 → XP_068078472.1  RNA-binding protein 4.1 isoform X1

    UniProtKB/Swiss-Prot
    Q6IQ97, Q7ZV02
    UniProtKB/TrEMBL
    A9JT29

  2. XM_009303078.4 → XP_009301353.1  RNA-binding protein 4.1 isoform X2

    UniProtKB/TrEMBL
    A0A1D5NSQ1, A0A8M3B123
    Related
    ENSDARP00000142868.1, ENSDART00000173633.2
    Conserved Domains (2) summary
    cd12606
    Location:2 → 68
    RRM1_RBM4; RNA recognition motif 1 in vertebrate RNA-binding protein 4 (RBM4)
    cl17169
    Location:78 → 138
    RRM_SF; RNA recognition motif (RRM) superfamily
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6IQ97.1 GenPept UniProtKB/Swiss-Prot:Q6IQ97

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