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muc5.2 mucin 5.2 [ Danio rerio (zebrafish) ]

Gene ID: 572172, updated on 4-Jan-2025

Summary

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Official Symbol
muc5.2provided by ZNC
Official Full Name
mucin 5.2provided by ZNC
Primary source
ZFIN:ZDB-GENE-121108-1
See related
Ensembl:ENSDARG00000058556 AllianceGenome:ZFIN:ZDB-GENE-121108-1
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
muc5b
Summary
Is expressed in pharynx. Human ortholog(s) of this gene implicated in bronchiolitis; dry eye syndrome; idiopathic pulmonary fibrosis; interstitial lung disease 2; and urinary bladder cancer. Orthologous to human MUC5AC (mucin 5AC, oligomeric mucus/gel-forming) and MUC5B (mucin 5B, oligomeric mucus/gel-forming). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
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Genomic context

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See muc5.2 in Genome Data Viewer
Location:
chromosome: 25
Exon count:
46
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (8407892..8445172)
105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (8330824..8368281)

Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene intestinal mucin-like protein Neighboring gene mucin 5.1, oligomeric mucus/gel-forming Neighboring gene FA complementation group I Neighboring gene polymerase (DNA directed), gamma Neighboring gene transfer RNA arginine (anticodon UCG)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Searching the Evolutionary Origin of Epithelial Mucus Protein Components-Mucins and FCGBP. Lang T, et al. Mol Biol Evol, 2016 Aug. PMID 27189557, Free PMC Article
  2. Zebrafish as a model to study live mucus physiology. Jevtov I, et al. Sci Rep, 2014 Oct 17. PMID 25323747, Free PMC Article
  3. Effects of the Essential Oil from Pistacia lentiscus Var. chia on the Lateral Line System and the Gene Expression Profile of Zebrafish (Danio rerio). Serifi I, et al. Molecules, 2019 Oct 30. PMID 31671694, Free PMC Article
  4. Role of the melanocortin system in zebrafish skin physiology. Leal E, et al. Fish Shellfish Immunol, 2022 Nov. PMID 36150411
  5. Deficiency in macrophage-stimulating protein results in spontaneous intestinal inflammation and increased susceptibility toward epithelial damage in zebrafish. Witte M, et al. Zebrafish, 2014 Dec. PMID 25353089

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

General protein information

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Preferred Names
mucin 5.2; mucin-2
Names
mucin 5b
unm_sa927

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007136.7 Reference GRCz11 Primary Assembly

    Range
    8407892..8445172
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068217494.1 → XP_068073595.1  mucin-2

    Related
    ENSDARP00000129173.1, ENSDART00000153536.3
Nucleotide Protein Strain
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