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siva1 SIVA1, apoptosis-inducing factor [ Danio rerio (zebrafish) ]

Gene ID: 571845, updated on 4-Jan-2025

Summary

Official Symbol
siva1provided by ZNC
Official Full Name
SIVA1, apoptosis-inducing factorprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050506-57
See related
Ensembl:ENSDARG00000114552 AllianceGenome:ZFIN:ZDB-GENE-050506-57
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
im:6902407
Summary
Predicted to enable CD27 receptor binding activity. Predicted to be involved in extrinsic apoptotic signaling pathway. Is expressed in male organism. Orthologous to human SIVA1 (SIVA1 apoptosis inducing factor). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See siva1 in Genome Data Viewer
Location:
chromosome: 17
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (1360044..1369344)
105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (699778..709078)

Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene inverted formin 2 Neighboring gene adenylosuccinate synthase 1 Neighboring gene zinc finger and BTB domain containing 42 Neighboring gene v-akt murine thymoma viral oncogene homolog 1

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables CD27 receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in extrinsic apoptotic signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
apoptosis regulatory protein Siva

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001327928.1NP_001314857.1  apoptosis regulatory protein Siva

    Status: VALIDATED

    Source sequence(s)
    CR855301, EH453280, EH453513, EH456122, EH510676
    UniProtKB/TrEMBL
    A0A2R8QL23, A0A8M1P8I3
    Related
    ENSDARP00000156081.1, ENSDART00000184561.1
    Conserved Domains (1) summary
    pfam05458
    Location:1171
    Siva; Cd27 binding protein (Siva)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007128.7 Reference GRCz11 Primary Assembly

    Range
    1360044..1369344
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)