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rad21l1 RAD21 cohesin complex component like 1 [ Danio rerio (zebrafish) ]

Gene ID: 571082, updated on 9-Dec-2024

Summary

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Official Symbol
rad21l1provided by ZNC
Official Full Name
RAD21 cohesin complex component like 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-061103-505
See related
Ensembl:ENSDARG00000022493 AllianceGenome:ZFIN:ZDB-GENE-061103-505
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:154013; CH1073-428E6.1
Summary
Predicted to enable chromatin binding activity. Predicted to be involved in replication-born double-strand break repair via sister chromatid exchange and sister chromatid cohesion. Predicted to act upstream of or within chromosome segregation. Predicted to be located in nucleus. Predicted to be part of cohesin complex. Orthologous to human RAD21L1 (RAD21 cohesin complex component like 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See rad21l1 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (49117518..49140645)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (49128749..49151876)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 Neighboring gene golgi membrane protein 1 Neighboring gene syntaphilin Neighboring gene FKBP prolyl isomerase 1Aa

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Rad21l1 cohesin subunit is dispensable for spermatogenesis but not oogenesis in zebrafish. Blokhina YP, et al. PLoS Genet, 2021 Jun. PMID 34138874, Free PMC Article
  2. Sycp2 is essential for synaptonemal complex assembly, early meiotic recombination and homologous pairing in zebrafish spermatocytes. Takemoto K, et al. PLoS Genet, 2020 Feb. PMID 32092049, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Rad21l1 cohesin subunit is dispensable for spermatogenesis but not oogenesis in zebrafish.
    Title: Rad21l1 cohesin subunit is dispensable for spermatogenesis but not oogenesis in zebrafish.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within chromosome segregation IEA
Inferred from Electronic Annotation
more info
  
involved_in replication-born double-strand break repair via sister chromatid exchange IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sister chromatid cohesion IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within sister chromatid cohesion IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of cohesin complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of cohesin complex IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
double-strand-break repair protein rad21-like protein 1
Names
RAD21-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080050.1 → NP_001073519.1  double-strand-break repair protein rad21-like protein 1

    See identical proteins and their annotated locations for NP_001073519.1

    Status: PROVISIONAL

    Source sequence(s)
    BC125933
    UniProtKB/TrEMBL
    A0A8N7UYI9, A0JMM5
    Related
    ENSDARP00000074083.4, ENSDART00000079631.5
    Conserved Domains (2) summary
    pfam04824
    Location:495 → 543
    Rad21_Rec8; Conserved region of Rad21 / Rec8 like protein
    pfam04825
    Location:1 → 100
    Rad21_Rec8_N; N terminus of Rad21 / Rec8 like protein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    49117518..49140645
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068223010.1 → XP_068079111.1  double-strand-break repair protein rad21-like protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8N7UYI9, A0JMM5
Nucleotide Protein
Heading Accession and Version

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