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zic2b - zic family member 2 (odd-paired homolog, Drosophila) b

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including brain development; embryonic viscerocranium morphogenesis; and regulation of retinoic acid receptor signaling pathway. Predicted to be active in nucleus. Is expressed in several structures, including germ ring; immature eye; nervous system; neural keel; and neural plate. Human ortholog(s) of this gene implicated in holoprosencephaly and holoprosencephaly 5. Orthologous to human ZIC2 (Zic family member 2). [provided by Alliance of Genome Resources, Nov 2024]

Genes similar to zic2b

NCBI Orthologs

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Species Gene Architecture aa