U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

cracd capping protein inhibiting regulator of actin dynamics [ Danio rerio (zebrafish) ]

Gene ID: 570321, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
cracdprovided by ZNC
Official Full Name
capping protein inhibiting regulator of actin dynamicsprovided by ZNC
Primary source
ZFIN:ZDB-GENE-041210-321
See related
Ensembl:ENSDARG00000011602 AllianceGenome:ZFIN:ZDB-GENE-041210-321
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
crad; wu:fi14c02; si:dkeyp-117h8.2
Summary
Predicted to be involved in maintenance of gastrointestinal epithelium and negative regulation of barbed-end actin filament capping. Predicted to be located in cytosol. Orthologous to human CRACD (capping protein inhibiting regulator of actin dynamics). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See cracd in Genome Data Viewer
Location:
chromosome: 20
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (25659953..25709356, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (25760863..25810260, complement)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene si:dkeyp-117h8.4 Neighboring gene aminoadipate-semialdehyde dehydrogenase Neighboring gene centrosomal protein 135 Neighboring gene carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  2. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • fi14c02

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in epithelial structure maintenance ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in maintenance of gastrointestinal epithelium IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in maintenance of gastrointestinal epithelium ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in negative regulation of barbed-end actin filament capping IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of barbed-end actin filament capping ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of actin filament polymerization ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
capping protein inhibiting regulator of actin dynamics
Names
cancer-related regulator of actin dynamics homolog

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001347676.1 → NP_001334605.1  capping protein inhibiting regulator of actin dynamics

    Status: VALIDATED

    Source sequence(s)
    CR352243
    UniProtKB/Swiss-Prot
    Q5RG44
    Related
    ENSDARP00000156539.1, ENSDART00000182775.1
    Conserved Domains (1) summary
    pfam15262
    Location:19 → 130
    DUF4592; Domain of unknown function (DUF4592)

  2. NM_001347678.1 → NP_001334607.1  capping protein inhibiting regulator of actin dynamics

    Status: VALIDATED

    Source sequence(s)
    CR352243
    UniProtKB/Swiss-Prot
    Q5RG44
    Related
    ENSDARP00000122314.2, ENSDART00000146711.4
    Conserved Domains (1) summary
    pfam15262
    Location:19 → 130
    DUF4592; Domain of unknown function (DUF4592)

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    25659953..25709356 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068215548.1 → XP_068071649.1  capping protein inhibiting regulator of actin dynamics isoform X2

    UniProtKB/TrEMBL
    A0A8M9PHI5

  2. XM_021468508.2 → XP_021324183.1  capping protein inhibiting regulator of actin dynamics isoform X1

    UniProtKB/TrEMBL
    A0A8M9PBX4
    Conserved Domains (1) summary
    pfam15262
    Location:127 → 238
    DUF4592; Domain of unknown function (DUF4592)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5RG44.3 GenPept UniProtKB/Swiss-Prot:Q5RG44

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.