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ensaa endosulfine alpha a [ Danio rerio (zebrafish) ]

Gene ID: 569530, updated on 4-Jan-2025

Summary

Official Symbol
ensaaprovided by ZNC
Official Full Name
endosulfine alpha aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060503-181
See related
Ensembl:ENSDARG00000036944 AllianceGenome:ZFIN:ZDB-GENE-060503-181
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
ensa; si:dkeyp-24a7.3
Summary
Predicted to enable protein phosphatase 2A binding activity and protein phosphatase inhibitor activity. Predicted to be involved in G2/M transition of mitotic cell cycle. Predicted to act upstream of or within cell division. Predicted to be active in cytoplasm. Is expressed in female organism. Orthologous to human ENSA (endosulfine alpha). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See ensaa in Genome Data Viewer
Location:
chromosome: 19
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (341992..346364)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (341770..343943)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene glycerol-3-phosphate dehydrogenase 1c Neighboring gene golgi phosphoprotein 3-like Neighboring gene MCL1 apoptosis regulator, BCL2 family member a Neighboring gene vacuolar protein sorting 72 homolog a

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables phosphatase inhibitor activity ISS
Inferred from Sequence or Structural Similarity
more info
 
enables protein phosphatase 2A binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables protein phosphatase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein phosphatase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 
enables protein phosphatase regulator activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
involved_in G2/M transition of mitotic cell cycle ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001045184.1NP_001038649.1  alpha-endosulfine

    See identical proteins and their annotated locations for NP_001038649.1

    Status: PROVISIONAL

    Source sequence(s)
    CR548627
    UniProtKB/Swiss-Prot
    B3DHK3, Q1L8X2
    Related
    ENSDARP00000149317.1, ENSDART00000187622.1
    Conserved Domains (1) summary
    pfam04667
    Location:40115
    Endosulfine; cAMP-regulated phosphoprotein/endosulfine conserved region

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    341992..346364
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005159315.5XP_005159372.1  alpha-endosulfine isoform X1

    See identical proteins and their annotated locations for XP_005159372.1

    UniProtKB/Swiss-Prot
    Q1L8X2
    Related
    ENSDARP00000125983.1, ENSDART00000151013.2
    Conserved Domains (1) summary
    pfam04667
    Location:29104
    Endosulfine; cAMP-regulated phosphoprotein/endosulfine conserved region