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cenps centromere protein S [ Danio rerio (zebrafish) ]

Gene ID: 569270, updated on 9-Dec-2024

Summary

Official Symbol
cenpsprovided by ZNC
Official Full Name
centromere protein Sprovided by ZNC
Primary source
ZFIN:ZDB-GENE-080723-52
See related
Ensembl:ENSDARG00000070485 AllianceGenome:ZFIN:ZDB-GENE-080723-52
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
apitd1; zgc:194319
Summary
Predicted to enable chromatin binding activity. Predicted to be involved in replication fork processing and resolution of meiotic recombination intermediates. Predicted to act upstream of or within DNA repair. Predicted to be part of FANCM-MHF complex. Orthologous to several human genes including CENPS (centromere protein S). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See cenps in Genome Data Viewer
Location:
chromosome: 6
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (45934724..45937000)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (45932842..45935118)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108190430 Neighboring gene hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) Neighboring gene TAR DNA binding protein b Neighboring gene retinol binding protein 7b, cellular Neighboring gene carbonic anhydrase XVI b Neighboring gene CFAP20 domain containing

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within DNA damage response IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within DNA repair IEA
Inferred from Electronic Annotation
more info
 
involved_in replication fork processing IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in resolution of meiotic recombination intermediates IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
part_of FANCM-MHF complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of FANCM-MHF complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
centromere protein S
Names
apoptosis-inducing, TAF9-like domain 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001128749.1NP_001122221.1  centromere protein S

    See identical proteins and their annotated locations for NP_001122221.1

    Status: PROVISIONAL

    Source sequence(s)
    BC163634
    UniProtKB/TrEMBL
    B3DJV8, B3DJW6, F6NV23
    Related
    ENSDARP00000094265.2, ENSDART00000103489.4
    Conserved Domains (1) summary
    pfam15630
    Location:984
    CENP-S; Kinetochore component CENP-S

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    45934724..45937000
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394666.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    31288..33564
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)