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pleca - plectin a

Predicted to enable ankyrin binding activity. Predicted to be a structural constituent of cytoskeleton. Acts upstream of or within locomotory behavior and skeletal muscle tissue development. Predicted to be located in cytoskeleton and membrane. Predicted to be active in several cellular components, including focal adhesion; hemidesmosome; and sarcolemma. Predicted to colocalize with intermediate filament. Is expressed in epidermis; telencephalon; and yolk syncytial layer. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy type 2Q; epidermolysis bullosa simplex; epidermolysis bullosa simplex Ogna type; and epidermolysis bullosa simplex with muscular dystrophy. Orthologous to human PLEC (plectin). [provided by Alliance of Genome Resources, Dec 2024]

Genes similar to pleca

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Species Gene Architecture aa