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arl8a ADP-ribosylation factor-like 8A [ Danio rerio (zebrafish) ]

Gene ID: 567222, updated on 2-Nov-2024

Summary

Official Symbol
arl8aprovided by ZNC
Official Full Name
ADP-ribosylation factor-like 8Aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-5025
See related
Ensembl:ENSDARG00000078686 AllianceGenome:ZFIN:ZDB-GENE-030131-5025
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fe25e11; wu:fe25e11; si:ch1073-204j4.2
Summary
Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in anterograde axonal transport. Predicted to act upstream of or within protein transport. Predicted to be located in late endosome membrane and lysosome. Predicted to be active in lysosomal membrane. Orthologous to human ARL8A (ADP ribosylation factor like GTPase 8A). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See arl8a in Genome Data Viewer
Location:
chromosome: 22
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (710759..718615, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (673036..680892, complement)

Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene E74-like factor 3 (ets domain transcription factor, epithelial-specific ) Neighboring gene G protein-coupled receptor 37 like 1a Neighboring gene zgc:162255 Neighboring gene zinc finger protein 76

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in anterograde axonal transport IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in endosome IEA
Inferred from Electronic Annotation
more info
 
located_in late endosome membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in lysosomal membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ADP-ribosylation factor-like protein 8A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001200020.1NP_001186949.1  ADP-ribosylation factor-like protein 8A

    See identical proteins and their annotated locations for NP_001186949.1

    Status: VALIDATED

    Source sequence(s)
    CT693669, CU539055, CU855848, EH500770
    UniProtKB/TrEMBL
    A0A8M1NXH5, F8W2P1
    Related
    ENSDARP00000124659.1, ENSDART00000149320.2
    Conserved Domains (1) summary
    cd04159
    Location:22180
    Arl10_like; Arf-like 9 (Arl9) and 10 (Arl10) GTPases

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007133.7 Reference GRCz11 Primary Assembly

    Range
    710759..718615 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)