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arhgef16 Rho guanine nucleotide exchange factor (GEF) 16 [ Danio rerio (zebrafish) ]

Gene ID: 567180, updated on 9-Dec-2024

Summary

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Official Symbol
arhgef16provided by ZNC
Official Full Name
Rho guanine nucleotide exchange factor (GEF) 16provided by ZNC
Primary source
ZFIN:ZDB-GENE-081104-446
See related
Ensembl:ENSDARG00000077114 AllianceGenome:ZFIN:ZDB-GENE-081104-446
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:dkeyp-100a1.3
Summary
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in regulation of actin cytoskeleton organization. Orthologous to human ARHGEF16 (Rho guanine nucleotide exchange factor 16). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
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Genomic context

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See arhgef16 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (47098992..47143911)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (47108503..47153360)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137496385 Neighboring gene hes family bHLH transcription factor 2, tandem duplicate 1 Neighboring gene espin Neighboring gene espin-like protein Neighboring gene si:dkeyp-100a1.6 Neighboring gene Y box binding protein 1 Neighboring gene peptidylprolyl isomerase H (cyclophilin H) Neighboring gene uncharacterized LOC101883933

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
rho guanine nucleotide exchange factor 16

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001123283.1 → NP_001116755.1  rho guanine nucleotide exchange factor 16

    Status: PROVISIONAL

    Source sequence(s)
    BX000472, CR792439, CT573138
    UniProtKB/TrEMBL
    A0A8M1NIJ7, B0S4U0
    Related
    ENSDARP00000112801.1, ENSDART00000142979.3
    Conserved Domains (4) summary
    cd01221
    Location:438 → 559
    PH_ephexin; Ephexin Pleckstrin homology (PH) domain
    pfam00169
    Location:451 → 556
    PH; PH domain
    pfam00621
    Location:237 → 416
    RhoGEF; RhoGEF domain
    cl17036
    Location:568 → 598
    SH3; Src Homology 3 domain superfamily

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    47098992..47143911
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005167281.5 → XP_005167338.1  rho guanine nucleotide exchange factor 16 isoform X1

    UniProtKB/TrEMBL
    A0A8M2BEQ4
    Conserved Domains (4) summary
    cd11938
    Location:586 → 639
    SH3_ARHGEF16_26; Src homology 3 domain of the Rho guanine nucleotide exchange factors ARHGEF16 and ARHGEF26
    cd01221
    Location:456 → 577
    PH_ephexin; Ephexin Pleckstrin homology (PH) domain
    pfam00169
    Location:469 → 574
    PH; PH domain
    pfam00621
    Location:255 → 434
    RhoGEF; RhoGEF domain
Nucleotide Protein Strain
Heading Accession and Version

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