U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

gja13.2 gap junction protein alpha 13.2 [ Danio rerio (zebrafish) ]

Gene ID: 566647, updated on 4-Jan-2025

Summary

Go to the top of the page Help
Official Symbol
gja13.2provided by ZNC
Official Full Name
gap junction protein alpha 13.2provided by ZNC
Primary source
ZFIN:ZDB-GENE-050303-1
See related
Ensembl:ENSDARG00000076789 AllianceGenome:ZFIN:ZDB-GENE-050303-1
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
gjae; cx20e; gja13; cx31.9; cx32.2; gja13.1; zgc:153825; si:dkey-261a18.5
Summary
Predicted to enable gap junction channel activity. Predicted to be involved in cell-cell signaling. Predicted to act upstream of or within cell communication. Predicted to be located in gap junction and plasma membrane. Predicted to be part of connexin complex. Human ortholog(s) of this gene implicated in coronary artery disease and myocardial infarction. Orthologous to human GJA4 (gap junction protein alpha 4). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See gja13.2 in Genome Data Viewer
Location:
chromosome: 20
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (40723940..40729364, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (40826830..40832254, complement)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137488590 Neighboring gene gap junction protein alpha 1b Neighboring gene gap junction protein alpha 12.2 Neighboring gene gap junction protein, alpha 12.1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Developmental regulation and expression of the zebrafish connexin43 gene. Chatterjee B, et al. Dev Dyn, 2005 Jul. PMID 15895415
  2. Mutations in connexin43 (GJA1) perturb bone growth in zebrafish fins. Iovine MK, et al. Dev Biol, 2005 Feb 1. PMID 15649473
  3. Identification of Novel Vascular Genes Downstream of Islet2 and Nr2f1b Transcription Factors. Li RF, et al. Biomedicines, 2022 May 27. PMID 35740282, Free PMC Article
  4. Phylogeny of teleost connexins reveals highly inconsistent intra- and interspecies use of nomenclature and misassemblies in recent teleost chromosome assemblies. Mikalsen SO, et al. BMC Genomics, 2020 Mar 11. PMID 32160866, Free PMC Article
  5. Wnt-PLC-IP(3)-Connexin-Ca(2+) axis maintains ependymal motile cilia in zebrafish spinal cord. Zhang J, et al. Nat Commun, 2020 Apr 20. PMID 32312952, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Clone Names

  • MGC153825, MGC194198

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables gap junction channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell communication IEA
Inferred from Electronic Annotation
more info
  
involved_in cell-cell signaling IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in anchoring junction IEA
Inferred from Electronic Annotation
more info
  
part_of connexin complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of connexin complex IEA
Inferred from Electronic Annotation
more info
  
located_in gap junction IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
gap junction Cx32.2 protein
Names
connexin 32.2
gap junction protein alpha 13.1
gap junction protein, alpha e

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001030210.2 → NP_001025381.2  gap junction Cx32.2 protein

    See identical proteins and their annotated locations for NP_001025381.2

    Status: PROVISIONAL

    Source sequence(s)
    BC122427
    UniProtKB/Swiss-Prot
    Q0P3V1, Q5TYN7, Q7T047
    UniProtKB/TrEMBL
    B3DHP8
    Related
    ENSDARP00000091787.2, ENSDART00000101014.4
    Conserved Domains (3) summary
    smart00037
    Location:44 → 76
    CNX; Connexin homologues
    smart01089
    Location:148 → 213
    Connexin_CCC; Gap junction channel protein cysteine-rich domain
    pfam00029
    Location:3 → 215
    Connexin; Connexin

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    40723940..40729364 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7T047.4 GenPept UniProtKB/Swiss-Prot:Q7T047

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools