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qng1 Q-nucleotide N-glycosylase 1 [ Danio rerio (zebrafish) ]

Gene ID: 566166, updated on 9-Dec-2024

Summary

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Official Symbol
qng1provided by ZNC
Official Full Name
Q-nucleotide N-glycosylase 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-070410-3
See related
Ensembl:ENSDARG00000041372 AllianceGenome:ZFIN:ZDB-GENE-070410-3
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:136564
Summary
Predicted to enable hydrolase activity, hydrolyzing N-glycosyl compounds. Predicted to be involved in tRNA-guanine transglycosylation. Orthologous to human QNG1 (Q-nucleotide N-glycosylase 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
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Genomic context

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See qng1 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (49730163..49743489, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (49741394..49754750, complement)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene RAS and EF-hand domain containing Neighboring gene FERM domain containing 3 Neighboring gene G kinase anchoring protein 1 Neighboring gene heterogeneous nuclear ribonucleoprotein K Neighboring gene RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. A Genetic Model to Study Increased Hexosamine Biosynthetic Flux. Hugo SE, et al. Endocrinology, 2017 Aug 1. PMID 28582574, Free PMC Article
  2. Evolution after Whole-Genome Duplication: Teleost MicroRNAs. Desvignes T, et al. Mol Biol Evol, 2021 Jul 29. PMID 33871629, Free PMC Article
  3. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC136564

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
  
enables hydrolase activity, hydrolyzing N-glycosyl compounds IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in tRNA-guanine transglycosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
queuosine 5'-phosphate N-glycosylase/hydrolase
NP_001077027.1
XP_005167380.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001083558.1 → NP_001077027.1  queuosine 5'-phosphate N-glycosylase/hydrolase

    See identical proteins and their annotated locations for NP_001077027.1

    Status: PROVISIONAL

    Source sequence(s)
    BC115180
    UniProtKB/TrEMBL
    A0A8M1NCL2, A4FUL9
    Related
    ENSDARP00000069326.4, ENSDART00000074840.5
    Conserved Domains (1) summary
    pfam10343
    Location:55 → 336
    Q_salvage; Potential Queuosine, Q, salvage protein family

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    49730163..49743489 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005167323.4 → XP_005167380.1  queuosine 5'-phosphate N-glycosylase/hydrolase isoform X1

    See identical proteins and their annotated locations for XP_005167380.1

    UniProtKB/TrEMBL
    A0A8M1NCL2, A4FUL9
    Conserved Domains (1) summary
    pfam10343
    Location:55 → 336
    Q_salvage; Potential Queuosine, Q, salvage protein family
Nucleotide Protein Strain
Heading Accession and Version

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