tspan3a tetraspanin 3a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: tspan3aprovided by ZNC
Official Full Name: tetraspanin 3aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-7787
See related: Ensembl:ENSDARG00000034753 AllianceGenome:ZFIN:ZDB-GENE-030131-7787
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fj34d08; wu:fj34d08; zgc:114050; si:dkey-24l11.4
Summary: Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including eye; fin; gonad; heart; and integument. Orthologous to human TSPAN3 (tetraspanin 3). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 18

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	18	NC_007129.7 (26899313..26920130)
105	previous assembly	GRCz10 (GCF_000002035.5)	18	NC_007129.6 (26916935..26937752)

Chromosome 18 - NC_007129.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: tetraspanin-3

Names: tetraspanin 3

NP_001020709.1

EC 2.7.10.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001025538.2 → NP_001020709.1 tetraspanin-3

See identical proteins and their annotated locations for NP_001020709.1

Status: VALIDATED

Source sequence(s)

BX470164

UniProtKB/TrEMBL

A0A8M1N787, Q4V915

Related

ENSDARP00000050229.5, ENSDART00000050230.6

Conserved Domains (2) summary

cd03163
Location:104 → 210

TM4SF8_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), TM4SF8_like subfamily. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment ...

pfam00335
Location:10 → 237

Tetraspannin; Tetraspanin family