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mllt1a MLLT1 super elongation complex subunit a [ Danio rerio (zebrafish) ]

Gene ID: 565484, updated on 4-Jan-2025

Summary

Official Symbol
mllt1aprovided by ZNC
Official Full Name
MLLT1 super elongation complex subunit aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-081105-45
See related
Ensembl:ENSDARG00000043185 AllianceGenome:ZFIN:ZDB-GENE-081105-45
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
mllt1; si:dkey-240a9.4
Summary
Predicted to enable chromatin binding activity and lysine-acetylated histone binding activity. Predicted to be involved in positive regulation of DNA-templated transcription. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of transcription elongation factor complex. Orthologous to human MLLT1 (MLLT1 super elongation complex subunit). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See mllt1a in Genome Data Viewer
Location:
chromosome: 8
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 8 NC_007119.7 (20194156..20230661, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 8 NC_007119.6 (20163167..20198613, complement)

Chromosome 8 - NC_007119.7Genomic Context describing neighboring genes Neighboring gene FCH and mu domain containing endocytic adaptor 1 Neighboring gene regulatory factor X, 2 (influences HLA class II expression) Neighboring gene acyl-CoA synthetase bubblegum family member 2 Neighboring gene alkaline ceramidase 1 Neighboring gene myosin IF

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables lysine-acetylated histone binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in positive regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of transcription elongation factor complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
protein ENL
Names
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 a
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1a

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007119.7 Reference GRCz11 Primary Assembly

    Range
    20194156..20230661 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005166938.5XP_005166995.1  protein ENL isoform X4

    UniProtKB/TrEMBL
    A0A8M2BEY9
    Conserved Domains (1) summary
    pfam03366
    Location:29109
    YEATS; YEATS family
  2. XM_009303913.4XP_009302188.1  protein ENL isoform X2

    UniProtKB/TrEMBL
    A0A8M3BBR5
    Conserved Domains (1) summary
    pfam03366
    Location:29109
    YEATS; YEATS family
  3. XM_688768.10XP_693860.6  protein ENL isoform X3

    UniProtKB/TrEMBL
    A0A8N7T7S1
    Conserved Domains (1) summary
    pfam03366
    Location:29109
    YEATS; YEATS family
  4. XM_009303912.4XP_009302187.1  protein ENL isoform X1

    UniProtKB/TrEMBL
    A0A8M3AV46, E9QEN8
    Related
    ENSDARP00000063399.5, ENSDART00000063400.7
    Conserved Domains (1) summary
    pfam03366
    Location:29109
    YEATS; YEATS family