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myo5ab myosin VAb [ Danio rerio (zebrafish) ]

Gene ID: 565267, updated on 9-Dec-2024

Summary

Official Symbol
myo5abprovided by ZNC
Official Full Name
myosin VAbprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050411-72
See related
Ensembl:ENSDARG00000025218 AllianceGenome:ZFIN:ZDB-GENE-050411-72
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
im:7152131
Summary
Predicted to enable actin filament binding activity and microfilament motor activity. Predicted to be involved in actin filament organization and vesicle transport along actin filament. Predicted to be part of myosin complex. Predicted to be active in several cellular components, including actin cytoskeleton; cytoplasm; and vesicle. Human ortholog(s) of this gene implicated in Griscelli syndrome type 1. Orthologous to human MYO5A (myosin VA). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See myo5ab in Genome Data Viewer
Location:
chromosome: 25
Exon count:
40
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 25 NC_007136.7 (7612256..7650464, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 25 NC_007136.6 (7438078..7475262, complement)

Chromosome 25 - NC_007136.7Genomic Context describing neighboring genes Neighboring gene fucose kinase Neighboring gene GTPase IMAP family member 8 Neighboring gene cAMP-regulated phosphoprotein 19b Neighboring gene Bet1 golgi vesicular membrane trafficking protein-like

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables actin binding IEA
Inferred from Electronic Annotation
more info
 
enables cytoskeletal motor activity IEA
Inferred from Electronic Annotation
more info
 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in system development IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of myosin complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
myosin VAb; unconventional myosin-Va

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007136.7 Reference GRCz11 Primary Assembly

    Range
    7612256..7650464 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009297774.4XP_009296049.2  unconventional myosin-Va isoform X1

    UniProtKB/TrEMBL
    A0A8M3API9
    Related
    ENSDARP00000083467.6, ENSDART00000089034.6
    Conserved Domains (3) summary
    cd01380
    Location:83742
    MYSc_Myo5; class V myosin, motor domain
    cl03379
    Location:14271800
    Myo5-like_CBD; Cargo binding domain of myosin 5 and similar proteins
    cl27381
    Location:71324
    Myosin_head; Myosin head (motor domain)
  2. XM_068217487.1XP_068073588.1  unconventional myosin-Va isoform X2