U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

si:ch1073-205c8.3 si:ch1073-205c8.3 [ Danio rerio (zebrafish) ]

Gene ID: 564377, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
si:ch1073-205c8.3provided by ZNC
Official Full Name
si:ch1073-205c8.3provided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-1059
See related
Ensembl:ENSDARG00000101521 AllianceGenome:ZFIN:ZDB-GENE-030131-1059
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
wu:fb58e05
Summary
Predicted to enable NEDD8 transferase activity. Predicted to be involved in protein neddylation. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including blastomere; central nervous system; eye; otic vesicle; and yolk. Orthologous to human UBE2M (ubiquitin conjugating enzyme E2 M). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See si:ch1073-205c8.3 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (48018797..48023764)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (48357710..48363497)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene zgc:158376 Neighboring gene catenin, beta 2 Neighboring gene E3 ubiquitin-protein ligase TRIM11 Neighboring gene karyopherin (importin) beta 1 Neighboring gene small nucleolar RNA SNORA79 Neighboring gene colony stimulating factor 3 (granulocyte) b

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  2. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables NEDD8 transferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in protein neddylation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
NEDD8-conjugating enzyme Ubc12
XP_001920670.3

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    48018797..48023764
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001920635.9 → XP_001920670.3  NEDD8-conjugating enzyme Ubc12

    UniProtKB/TrEMBL
    A0A0R4IUU4, A0A8M1QUV9
    Related
    ENSDARP00000138225.1, ENSDART00000172307.2
    Conserved Domains (2) summary
    COG5078
    Location:28 → 173
    COG5078; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
    pfam00179
    Location:35 → 168
    UQ_con; Ubiquitin-conjugating enzyme
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials