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ubap2a ubiquitin associated protein 2a [ Danio rerio (zebrafish) ]

Gene ID: 563733, updated on 27-Dec-2024

Summary

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Official Symbol
ubap2aprovided by ZNC
Official Full Name
ubiquitin associated protein 2aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-070424-16
See related
Ensembl:ENSDARG00000088318 AllianceGenome:ZFIN:ZDB-GENE-070424-16
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
ubap2; zgc:158449
Summary
Predicted to be located in cytoplasm. Orthologous to human UBAP2 (ubiquitin associated protein 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
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Genomic context

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See ubap2a in Genome Data Viewer
Location:
chromosome: 21
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (11916806..11955313)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (11824136..11862685)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene ubiquitin associated protein 1 Neighboring gene DDB1 and CUL4 associated factor 12 Neighboring gene small nucleolar RNA SNORD57 Neighboring gene NOP56 ribonucleoprotein homolog Neighboring gene motilin-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. UBAP2 plays a role in bone homeostasis through the regulation of osteoblastogenesis and osteoclastogenesis. Kim J, et al. Nat Commun, 2023 Jun 20. PMID 37339951, Free PMC Article
  2. Xmrk, kras and myc transgenic zebrafish liver cancer models share molecular signatures with subsets of human hepatocellular carcinoma. Zheng W, et al. PLoS One, 2014. PMID 24633177, Free PMC Article
  3. Drug screening in Scn1a zebrafish mutant identifies clemizole as a potential Dravet syndrome treatment. Baraban SC, et al. Nat Commun, 2013. PMID 24002024, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC158449

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ubiquitin-associated protein 2a
Names
ubiquitin associated protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001082838.2 → NP_001076307.2  ubiquitin-associated protein 2a

    Status: VALIDATED

    Source sequence(s)
    CT027620
    UniProtKB/TrEMBL
    A3KNA8
    Related
    ENSDARP00000120498.1, ENSDART00000136103.3

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    11916806..11955313
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017352809.3 → XP_017208298.1  ubiquitin-associated protein 2a isoform X1

    UniProtKB/TrEMBL
    A0A8M6Z3P0, A3KNA8

  2. XM_017352810.3 → XP_017208299.1  ubiquitin-associated protein 2a isoform X2

    UniProtKB/TrEMBL
    A0A8M6YUH8, A3KNA8

  3. XM_005161057.5 → XP_005161114.1  ubiquitin-associated protein 2a isoform X4

    UniProtKB/TrEMBL
    A0A8M2B877, A3KNA8
    Conserved Domains (2) summary
    cd14277
    Location:52 → 89
    UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
    pfam12478
    Location:509 → 538
    DUF3697; Ubiquitin-associated protein 2

  4. XM_017352811.3 → XP_017208300.1  ubiquitin-associated protein 2a isoform X3

    UniProtKB/TrEMBL
    A0A8M6Z309, A3KNA8

  5. XM_009295212.4 → XP_009293487.1  ubiquitin-associated protein 2a isoform X5

    UniProtKB/TrEMBL
    A0A8M3B4J7, A3KNA8
    Conserved Domains (2) summary
    cd14277
    Location:52 → 89
    UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
    pfam12478
    Location:507 → 536
    DUF3697; Ubiquitin-associated protein 2

  6. XM_009295213.4 → XP_009293488.1  ubiquitin-associated protein 2a isoform X6

    UniProtKB/TrEMBL
    A0A8M3AM03, A3KNA8
    Conserved Domains (2) summary
    cd14277
    Location:52 → 89
    UBA_UBP2_like; UBA domain found in ubiquitin-associated protein 2 (UBAP-2) like proteins
    pfam12478
    Location:507 → 536
    DUF3697; Ubiquitin-associated protein 2
Nucleotide Protein
Heading Accession and Version

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