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tbc1d9 TBC1 domain family, member 9 (with GRAM domain) [ Danio rerio (zebrafish) ]

Gene ID: 563578, updated on 9-Dec-2024

Summary

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Official Symbol
tbc1d9provided by ZNC
Official Full Name
TBC1 domain family, member 9 (with GRAM domain)provided by ZNC
Primary source
ZFIN:ZDB-GENE-060810-33
See related
Ensembl:ENSDARG00000059900 AllianceGenome:ZFIN:ZDB-GENE-060810-33
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
im:7148955; si:ch211-199c19.3
Summary
Predicted to enable GTPase activator activity. Is expressed in EVL; central nervous system; cranial ganglion; and trigeminal placode. Orthologous to human TBC1D9 (TBC1 domain family member 9). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
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Genomic context

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See tbc1d9 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (53321412..53365245)
105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (52686658..52726252)

Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 330 Neighboring gene ring finger protein 150a Neighboring gene uncoupling protein 1 Neighboring gene ELMO/CED-12 domain containing 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Adaptive evolution of the uncoupling protein 1 gene contributed to the acquisition of novel nonshivering thermogenesis in ancestral eutherian mammals. Saito S, et al. Gene, 2008 Jan 31. PMID 18023297
  2. Uncoupling protein 1 in fish uncovers an ancient evolutionary history of mammalian nonshivering thermogenesis. Jastroch M, et al. Physiol Genomics, 2005 Jul 14. PMID 15886331
  3. Exploring uncoupling proteins and antioxidant mechanisms under acute cold exposure in brains of fish. Tseng YC, et al. PLoS One, 2011 Mar 25. PMID 21464954, Free PMC Article
  4. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTPase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
  
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
TBC1 domain family member 9

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007112.7 Reference GRCz11 Primary Assembly

    Range
    53321412..53365245
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_686942.10 → XP_692034.2  TBC1 domain family member 9

    UniProtKB/TrEMBL
    A0A8N7TDD1, F1Q7J9
    Related
    ENSDARP00000115027.2, ENSDART00000143909.3
    Conserved Domains (3) summary
    smart00164
    Location:510 → 720
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    cd13354
    Location:301 → 396
    PH-GRAM2_TCB1D9_TCB1D9B; TBC1 domain family members 9 and 9B (TBC1D9 and TBC1D9B) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 2
    cd13351
    Location:154 → 252
    PH-GRAM1_TCB1D9_TCB1D9B; TBC1 domain family members 9 and 9B (TBC1D9 and TBC1D9B) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain, repeat 1
Nucleotide Protein Strain
Heading Accession and Version

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