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mllt11 MLLT11 transcription factor 7 cofactor [ Danio rerio (zebrafish) ]

Gene ID: 563531, updated on 9-Dec-2024

Summary

Official Symbol
mllt11provided by ZNC
Official Full Name
MLLT11 transcription factor 7 cofactorprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-3007
See related
Ensembl:ENSDARG00000071026 AllianceGenome:ZFIN:ZDB-GENE-030131-3007
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fc23g02; wu:fc23g02; si:ch211-210h11.4
Summary
Predicted to act upstream of or within apoptotic signaling pathway. Predicted to be located in centrosome; cytoplasm; and nucleus. Is expressed in cranial ganglion; neurons; retina; retinal ganglion cell layer; and trigeminal placode. Orthologous to human MLLT11 (MLLT11 transcription factor 7 cofactor). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See mllt11 in Genome Data Viewer
Location:
chromosome: 19
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (7445644..7450792, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (7526719..7531867, complement)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene splicing factor 3b, subunit 4 Neighboring gene GA binding protein transcription factor subunit beta 2a Neighboring gene MINDY lysine 48 deubiquitinase 1 Neighboring gene regulatory factor X, 5

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
acts_upstream_of_or_within apoptotic signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of mitochondrial depolarization IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in positive regulation of release of cytochrome c from mitochondria IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in centrosome IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein AF1q
Names
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001159984.2NP_001153456.1  protein AF1q

    See identical proteins and their annotated locations for NP_001153456.1

    Status: VALIDATED

    Source sequence(s)
    EH476290, EH588542, FP085396
    UniProtKB/Swiss-Prot
    A3KQS5
    Related
    ENSDARP00000095520.3, ENSDART00000104750.5
    Conserved Domains (1) summary
    pfam15017
    Location:269
    AF1Q; Drug resistance and apoptosis regulator

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    7445644..7450792 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)