podxl podocalyxin-like [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: podxlprovided by ZNC
Official Full Name: podocalyxin-likeprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-2805
See related: Ensembl:ENSDARG00000031228 AllianceGenome:ZFIN:ZDB-GENE-030131-2805
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fc18d02; wu:fc18d02; si:dkey-146n1.1
Summary: Acts upstream of or within pronephric glomerulus morphogenesis. Predicted to be located in several cellular components, including lamellipodium; membrane raft; and ruffle. Predicted to be active in apical plasma membrane and microvillus membrane. Is expressed in cardiovascular system; hindbrain neural keel; pronephros; and yolk syncytial layer. Orthologous to human PODXL (podocalyxin like). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 4

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	4	NC_007115.7 (11732156..11751054, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	4	NC_007115.6 (11733307..11752188, complement)

Chromosome 4 - NC_007115.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fc18d02.x1 (e-PCR)
- UniSTS:192852

fd60g02.y1 (e-PCR)
- UniSTS:195807

Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell adhesion	IEA Inferred from Electronic Annotation more info
involved_in cell migration	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within cell migration	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of cell-cell adhesion	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of cell-cell adhesion mediated by integrin	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within pronephric glomerulus morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of cell-cell adhesion	IEA Inferred from Electronic Annotation more info
involved_in regulation of microvillus assembly	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in apical plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in cell projection	IEA Inferred from Electronic Annotation more info
located_in filopodium	IEA Inferred from Electronic Annotation more info
located_in lamellipodium	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in membrane raft	IEA Inferred from Electronic Annotation more info
is_active_in microvillus membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in ruffle	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: podocalyxin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.