U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

wasf3a WASP family member 3a [ Danio rerio (zebrafish) ]

Gene ID: 562750, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
wasf3aprovided by ZNC
Official Full Name
WASP family member 3aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060531-55
See related
AllianceGenome:ZFIN:ZDB-GENE-060531-55
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
si:ch211-271b14.7
Summary
Predicted to enable Arp2/3 complex binding activity and protein kinase A regulatory subunit binding activity. Predicted to be involved in actin cytoskeleton organization and positive regulation of Arp2/3 complex-mediated actin nucleation. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be part of SCAR complex. Predicted to be active in lamellipodium. Orthologous to human WASF3 (WASP family member 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See wasf3a in Genome Data Viewer
Location:
chromosome: 5
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (68000712..68027036, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (67328519..67348143, complement)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene mitochondrial translational initiation factor 3 Neighboring gene general transcription factor IIIAa Neighboring gene ring finger protein 167 Neighboring gene sperm associated antigen 7

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. The cellular architecture and molecular determinants of the zebrafish fusogenic synapse. Luo Z, et al. Dev Cell, 2022 Jul 11. PMID 35709765, Free PMC Article
  2. Duplication and subfunctionalisation of the general transcription factor IIIA (gtf3a) gene in teleost genomes, with ovarian specific transcription of gtf3ab. Rojo-Bartolomé I, et al. PLoS One, 2020. PMID 31999691, Free PMC Article
  3. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
actin-binding protein WASF3
Names
WAS protein family, member 3a

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    68000712..68027036 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009301998.4 → XP_009300273.1  actin-binding protein WASF3

    UniProtKB/TrEMBL
    A0A8M3ASY4
    Conserved Domains (1) summary
    pfam02205
    Location:416 → 436
    WH2; WH2 motif

  2. XM_021476684.2 → XP_021332359.1  actin-binding protein WASF3

    UniProtKB/TrEMBL
    A0A8M3ASY4
    Conserved Domains (1) summary
    pfam02205
    Location:416 → 436
    WH2; WH2 motif
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools