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rab11fip5a RAB11 family interacting protein 5a (class I) [ Danio rerio (zebrafish) ]

Gene ID: 562719, updated on 4-Jan-2025

Summary

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Official Symbol
rab11fip5aprovided by ZNC
Official Full Name
RAB11 family interacting protein 5a (class I)provided by ZNC
Primary source
ZFIN:ZDB-GENE-090313-206
See related
Ensembl:ENSDARG00000104179 AllianceGenome:ZFIN:ZDB-GENE-090313-206
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
rab11fip5; si:dkey-187a3.1
Summary
Predicted to enable small GTPase binding activity. Acts upstream of or within digestive tract development; microvillus organization; and terminal web assembly. Predicted to be located in membrane. Is expressed in intestine; notochord; and spinal cord. Orthologous to human RAB11FIP5 (RAB11 family interacting protein 5). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See rab11fip5a in Genome Data Viewer
Location:
chromosome: 13
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (15088131..15142439, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (14957139..15012278, complement)

Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene empty spiracles homeobox 1 Neighboring gene sideroflexin 5a Neighboring gene zmp:0000000801 Neighboring gene mitochondrial antiviral signaling protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. The Rab11 effectors Fip5 and Fip1 regulate zebrafish intestinal development. Jewett CE, et al. Biol Open, 2020 Oct 23. PMID 32973079, Free PMC Article
  2. The novel human HtrA2 ortholog in zebrafish: New molecular insight and challenges into the imbalance of homeostasis. Nam MK, et al. Gene, 2022 Apr 20. PMID 35121025
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables small GTPase binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within digestive tract development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within microvillus organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within terminal web assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
rab11 family-interacting protein 5; serine-rich adhesin for platelets
Names
RAB11 family interacting protein 5 (class I)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007124.7 Reference GRCz11 Primary Assembly

    Range
    15088131..15142439 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009307214.4 → XP_009305489.1  rab11 family-interacting protein 5 isoform X2

    UniProtKB/TrEMBL
    A0A8M3AYZ9
    Related
    ENSDARP00000138627.1, ENSDART00000163132.2
    Conserved Domains (2) summary
    pfam09457
    Location:597 → 646
    RBD-FIP; FIP domain
    cl14603
    Location:17 → 149
    C2; C2 domain

  2. XM_009307211.4 → XP_009305486.1  serine-rich adhesin for platelets isoform X1

    UniProtKB/TrEMBL
    A0A8M3B546
    Conserved Domains (2) summary
    pfam09457
    Location:1562 → 1611
    RBD-FIP; FIP domain
    cl14603
    Location:17 → 149
    C2; C2 domain

  3. XM_009307215.4 → XP_009305490.1  rab11 family-interacting protein 5 isoform X3

    UniProtKB/TrEMBL
    A0A8M3BEJ7
    Conserved Domains (1) summary
    cl14603
    Location:17 → 149
    C2; C2 domain

  4. XM_021480767.2 → XP_021336442.1  rab11 family-interacting protein 5 isoform X4

    UniProtKB/TrEMBL
    A0A8M9PYF8
    Conserved Domains (1) summary
    cl14603
    Location:17 → 149
    C2; C2 domain
Nucleotide Protein Strain
Heading Accession and Version

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