mpp2a MAGUK p55 scaffold protein 2a [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: mpp2aprovided by ZNC
Official Full Name: MAGUK p55 scaffold protein 2aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-071004-82
See related: Ensembl:ENSDARG00000053453 AllianceGenome:ZFIN:ZDB-GENE-071004-82
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:171280
Summary: Predicted to be located in membrane. Predicted to be active in cell-cell junction and plasma membrane. Orthologous to human MPP2 (MAGUK p55 scaffold protein 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 3

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	3	NC_007114.7 (33345348..33379440)
105	previous assembly	GRCz10 (GCF_000002035.5)	3	NC_007114.6 (33213634..33247726)

Chromosome 3 - NC_007114.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
is_active_in cell-cell junction	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cellular_component	ND No biological Data available more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: MAGUK p55 subfamily member 2a

Names: membrane palmitoylated protein 2a; membrane protein, palmitoylated 2a (MAGUK p55 subfamily member 2); membrane protein, palmitoylated 2a (MAGUK p55 subfamily member 2a)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001327790.1 → NP_001314719.1 MAGUK p55 subfamily member 2a

Status: VALIDATED

Source sequence(s)

CABZ01012959, CABZ01012961, CABZ01012962

UniProtKB/TrEMBL

A0A8M9PW92, F1QV76

Related

ENSDARP00000059261.6, ENSDART00000059262.7

Conserved Domains (4) summary

cd00992
Location:134 → 212

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam02828
Location:62 → 113

L27; L27 domain

cl17036
Location:225 → 283

SH3; Src Homology 3 domain superfamily

cl27059
Location:344 → 534

Guanylate_kin; Guanylate kinase

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007114.7 Reference GRCz11 Primary Assembly

Range

33345348..33379440

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001109711.1: Suppressed sequence

Description

NM_001109711.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.