gra granulito [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: graprovided by ZNC
Official Full Name: granulitoprovided by ZNC
Primary source: ZFIN:ZDB-GENE-081022-203
See related: Ensembl:ENSDARG00000078754 AllianceGenome:ZFIN:ZDB-GENE-081022-203
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:195256; zgc:195266
Summary: Predicted to enable eukaryotic initiation factor 4E binding activity. Predicted to be involved in negative regulation of translational initiation. Predicted to act upstream of or within negative regulation of translation. Located in P granule. Is expressed in blastomere and primordial germ cell. Orthologous to human C8orf88 (chromosome 8 open reading frame 88). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (16222394..16226220, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (16314417..16318243, complement)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables eukaryotic initiation factor 4E binding	IBA Inferred from Biological aspect of Ancestor more info
enables eukaryotic initiation factor 4E binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within negative regulation of translation	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of translational initiation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within negative regulation of translational initiation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of translation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in P granule	IDA Inferred from Direct Assay more info	PubMed
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: uncharacterized protein C8orf88 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.