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nectin4a nectin cell adhesion molecule 4a [ Danio rerio (zebrafish) ]

Gene ID: 560512, updated on 9-Dec-2024

Summary

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Official Symbol
nectin4aprovided by ZNC
Official Full Name
nectin cell adhesion molecule 4aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-160728-55
See related
Ensembl:ENSDARG00000077419 AllianceGenome:ZFIN:ZDB-GENE-160728-55
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
nectin4; si:ch211-119e14.9
Summary
Predicted to be located in plasma membrane. Orthologous to human NECTIN4 (nectin cell adhesion molecule 4). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See nectin4a in Genome Data Viewer
Location:
chromosome: 7
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (18657007..18700426, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (18405741..18448204, complement)

Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene si:ch211-119e14.1 Neighboring gene coronin, actin binding protein, 1B Neighboring gene tRNA methyltransferase 10A Neighboring gene si:dkey-38l22.2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in homophilic cell adhesion via plasma membrane adhesion molecules IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in adherens junction IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
nectin-4
Names
nectin cell adhesion molecule 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007118.7 Reference GRCz11 Primary Assembly

    Range
    18657007..18700426 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017356997.3 → XP_017212486.1  nectin-4 isoform X2

    UniProtKB/TrEMBL
    A0A8M6YZC9
    Related
    ENSDARP00000148027.1, ENSDART00000183715.1

  2. XM_683919.9 → XP_689011.4  nectin-4 isoform X1

    UniProtKB/TrEMBL
    A0A8N7UT04, E7F9P1
    Related
    ENSDARP00000098890.2, ENSDART00000112359.6
    Conserved Domains (2) summary
    smart00410
    Location:44 → 144
    IG_like; Immunoglobulin like
    cl11960
    Location:45 → 145
    Ig; Immunoglobulin domain
Nucleotide Protein
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