pgm5 phosphoglucomutase 5 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: pgm5provided by ZNC
Official Full Name: phosphoglucomutase 5provided by ZNC
Primary source: ZFIN:ZDB-GENE-060503-838
See related: Ensembl:ENSDARG00000060745 AllianceGenome:ZFIN:ZDB-GENE-060503-838
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:dkey-91m11.4
Summary: Predicted to enable phosphoglucomutase activity. Acts upstream of or within myofibril assembly and striated muscle tissue development. Predicted to be active in several cellular components, including adherens junction; cell-substrate junction; and sarcolemma. Is expressed in gut; head; and somite. Orthologous to human PGM5 (phosphoglucomutase 5). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 8

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	8	NC_007119.7 (30456161..30494617)
105	previous assembly	GRCz10 (GCF_000002035.5)	8	NC_007119.6 (30446929..30485385)

Chromosome 8 - NC_007119.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fkd8 (e-PCR)
- UniSTS:205629

fa11f07.s1 (e-PCR)
- UniSTS:202317

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables intramolecular phosphotransferase activity	IEA Inferred from Electronic Annotation more info
NOT enables phosphoglucomutase activity	IBA Inferred from Biological aspect of Ancestor more info
enables phosphoglucomutase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in carbohydrate metabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
involved_in myofibril assembly	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within myofibril assembly	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in striated muscle tissue development	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within striated muscle tissue development	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in adherens junction	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cell-substrate junction	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
is_active_in sarcolemma	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: phosphoglucomutase-like protein 5

Names: aciculin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001126396.1 → NP_001119868.1 phosphoglucomutase-like protein 5

Status: PROVISIONAL

Source sequence(s)

AL845168

UniProtKB/TrEMBL

A0A8M1NGN0, B0R0B3

Related

ENSDARP00000080329.4, ENSDART00000085894.5

Conserved Domains (2) summary

PLN02307
Location:6 → 567

PLN02307; phosphoglucomutase

cl03757
Location:10 → 567

phosphohexomutase; The alpha-D-phosphohexomutase superfamily includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Members of this family include the phosphoglucomutases (PGM1 and PGM2), phosphoglucosamine ...