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dok1a docking protein 1a [ Danio rerio (zebrafish) ]

Gene ID: 559168, updated on 27-Dec-2024

Summary

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Official Symbol
dok1aprovided by ZNC
Official Full Name
docking protein 1aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-080721-2
See related
Ensembl:ENSDARG00000078108 AllianceGenome:ZFIN:ZDB-GENE-080721-2
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to be involved in Ras protein signal transduction and cell surface receptor protein tyrosine kinase signaling pathway. Predicted to be active in cytoplasm. Orthologous to human DOK1 (docking protein 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See dok1a in Genome Data Viewer
Location:
chromosome: 1
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (41478345..41485335)
105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (40775454..40782191)

Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene transfer RNA glutamic acid (anticodon CUC) Neighboring gene poly(A) binding protein interacting protein 2B Neighboring gene si:ch211-89o9.6 Neighboring gene transfer RNA lysine (anticodon CUU)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Comparative genomics of Lbx loci reveals conservation of identical Lbx ohnologs in bony vertebrates. Wotton KR, et al. BMC Evol Biol, 2008 Jun 9. PMID 18541024, Free PMC Article
  2. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
  3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in Ras protein signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cell surface receptor protein tyrosine kinase signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
docking protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007112.7 Reference GRCz11 Primary Assembly

    Range
    41478345..41485335
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_682484.9 → XP_687576.4  docking protein 2

    UniProtKB/TrEMBL
    A0A8N7USX8, F6P620
    Related
    ENSDARP00000113679.2, ENSDART00000134626.3
    Conserved Domains (2) summary
    pfam00169
    Location:6 → 114
    PH; PH domain
    cl17171
    Location:143 → 241
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein Strain
Heading Accession and Version

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