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myo18ab myosin XVIIIA b [ Danio rerio (zebrafish) ]

Gene ID: 559005, updated on 9-Dec-2024

Summary

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Official Symbol
myo18abprovided by ZNC
Official Full Name
myosin XVIIIA bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-080423-1
See related
Ensembl:ENSDARG00000061862 AllianceGenome:ZFIN:ZDB-GENE-080423-1
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
tiaf1; myo18l1; wu:fb52c07; si:ch211-103e6.2
Summary
Predicted to enable actin filament binding activity. Acts upstream of or within several processes, including Golgi organization; muscle tissue morphogenesis; and striated muscle cell development. Predicted to be part of myosin II complex. Predicted to be active in cytoplasm and myosin filament. Is expressed in head; notochord; skeletal muscle cell; and somite. Orthologous to human MYO18A (myosin XVIIIA). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
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Genomic context

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See myo18ab in Genome Data Viewer
Location:
chromosome: 15
Exon count:
52
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (23947959..24120972)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (24012681..24185652)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene si:ch1073-145m9.1 Neighboring gene amyloid beta precursor protein (cytoplasmic tail) binding protein 2 Neighboring gene pipecolic acid oxidase Neighboring gene seizure related 6 homolog b Neighboring gene uncharacterized LOC108179305

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. The PDZ-containing unconventional myosin XVIIIA regulates embryonic muscle integrity in zebrafish. Cao J, et al. J Genet Genomics, 2014 Aug 20. PMID 25160974
  2. Identification of novel MYO18A interaction partners required for myoblast adhesion and muscle integrity. Cao JM, et al. Sci Rep, 2016 Nov 8. PMID 27824130, Free PMC Article
  3. Genome wide association and genomic prediction for growth traits in juvenile farmed Atlantic salmon using a high density SNP array. Tsai HY, et al. BMC Genomics, 2015 Nov 18. PMID 26582102, Free PMC Article
  4. Expression of unconventional myosin genes during neuronal development in zebrafish. Sittaramane V, et al. Gene Expr Patterns, 2008 Feb. PMID 18078791, Free PMC Article
  5. A comparative map of the zebrafish genome. Woods IG, et al. Genome Res, 2000 Dec. PMID 11116086, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables actin binding IEA
Inferred from Electronic Annotation
more info
  
enables cytoskeletal motor activity IEA
Inferred from Electronic Annotation
more info
  
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within Golgi organization IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within cell-matrix adhesion IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within muscle tissue morphogenesis IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within muscle tissue morphogenesis IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within skeletal muscle fiber development IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within skeletal muscle fiber development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within skeletal myofibril assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in system development IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of myosin complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
myosin-XVIIIa; unconventional myosin-XVIIIa
Names
TGFB1-induced anti-apoptotic factor 1
myo18a
myosin XVIII-like 1
myosin XVIIIAb

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    23947959..24120972
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_068213726.1 → XP_068069827.1  unconventional myosin-XVIIIa isoform X1

    UniProtKB/TrEMBL
    A0A8M9NYM9

  2. XM_068213735.1 → XP_068069836.1  unconventional myosin-XVIIIa isoform X9

  3. XM_068213745.1 → XP_068069846.1  unconventional myosin-XVIIIa isoform X19

  4. XM_068213736.1 → XP_068069837.1  unconventional myosin-XVIIIa isoform X10

    UniProtKB/TrEMBL
    A0A8M3APY2

  5. XM_068213737.1 → XP_068069838.1  unconventional myosin-XVIIIa isoform X11

    UniProtKB/TrEMBL
    A0A8M3APY2
    Related
    ENSDARP00000128019.1, ENSDART00000153951.3

  6. XM_068213738.1 → XP_068069839.1  unconventional myosin-XVIIIa isoform X12

    UniProtKB/TrEMBL
    A0A8M3AHI6

  7. XM_068213739.1 → XP_068069840.1  unconventional myosin-XVIIIa isoform X13

    UniProtKB/TrEMBL
    A0A8M9PIP0

  8. XM_068213740.1 → XP_068069841.1  unconventional myosin-XVIIIa isoform X14

    UniProtKB/TrEMBL
    A0A8M6YT96

  9. XM_068213725.1 → XP_068069826.1  unconventional myosin-XVIIIa isoform X1

    UniProtKB/TrEMBL
    A0A8M9NYM9

  10. XM_068213741.1 → XP_068069842.1  unconventional myosin-XVIIIa isoform X15

    UniProtKB/TrEMBL
    A0A8M9NYM9, A0A8M9P7A8

  11. XM_068213730.1 → XP_068069831.1  unconventional myosin-XVIIIa isoform X4

    UniProtKB/TrEMBL
    A0A8M9NYM9

  12. XM_068213742.1 → XP_068069843.1  unconventional myosin-XVIIIa isoform X16

    UniProtKB/TrEMBL
    A0A8M9NYM9, A0A8M9PCE1

  13. XM_068213728.1 → XP_068069829.1  unconventional myosin-XVIIIa isoform X2

    UniProtKB/TrEMBL
    A0A8M9NYM9

  14. XM_068213731.1 → XP_068069832.1  unconventional myosin-XVIIIa isoform X5

    UniProtKB/TrEMBL
    A0A8M9NYM9

  15. XM_068213729.1 → XP_068069830.1  unconventional myosin-XVIIIa isoform X3

    UniProtKB/TrEMBL
    A0A8M9NYM9

  16. XM_068213732.1 → XP_068069833.1  unconventional myosin-XVIIIa isoform X6

    UniProtKB/TrEMBL
    A0A8M9NYM9

  17. XM_068213733.1 → XP_068069834.1  unconventional myosin-XVIIIa isoform X7

    UniProtKB/TrEMBL
    A0A8M9NYM9

  18. XM_068213734.1 → XP_068069835.1  unconventional myosin-XVIIIa isoform X8

    UniProtKB/TrEMBL
    A0A8M9PLN0

  19. XM_068213743.1 → XP_068069844.1  unconventional myosin-XVIIIa isoform X17

  20. XM_068213727.1 → XP_068069828.1  unconventional myosin-XVIIIa isoform X1

    UniProtKB/TrEMBL
    A0A8M9NYM9
    Related
    ENSDARP00000083081.5, ENSDART00000088648.6

  21. XM_068213744.1 → XP_068069845.1  unconventional myosin-XVIIIa isoform X18

Nucleotide Protein Strain
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