U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

taf15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor [ Danio rerio (zebrafish) ]

Gene ID: 558760, updated on 9-Dec-2024

Summary

Go to the top of the page Help
Official Symbol
taf15provided by ZNC
Official Full Name
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factorprovided by ZNC
Primary source
ZFIN:ZDB-GENE-061215-102
See related
Ensembl:ENSDARG00000070019 AllianceGenome:ZFIN:ZDB-GENE-061215-102
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fa11g05; wu:fa11g05; wu:fc02g02; zgc:158363
Summary
Predicted to enable RNA binding activity and transcription coregulator activity. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in chondrosarcoma and extraskeletal myxoid chondrosarcoma. Orthologous to human TAF15 (TATA-box binding protein associated factor 15). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See taf15 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (1825176..1843841, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (1861604..1880282, complement)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene cullin 3b Neighboring gene family with sequence similarity 124 member B Neighboring gene matrix metallopeptidase 28 Neighboring gene P450 (cytochrome) oxidoreductase b Neighboring gene SBDS ribosome maturation factor

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Reversible and Irreversible Aggregation of Proteins from the FET Family: Influence of Repeats in Protein Chain on Its Aggregation Capacity. Galzitskaya OV. Curr Protein Pept Sci, 2016. PMID 26100283
  2. CRISPR-Cpf1 mediates efficient homology-directed repair and temperature-controlled genome editing. Moreno-Mateos MA, et al. Nat Commun, 2017 Dec 8. PMID 29222508, Free PMC Article
  3. Codon identity regulates mRNA stability and translation efficiency during the maternal-to-zygotic transition. Bazzini AA, et al. EMBO J, 2016 Oct 4. PMID 27436874, Free PMC Article
  4. Functional characterization of a FUS mutant zebrafish line as a novel genetic model for ALS. Bourefis AR, et al. Neurobiol Dis, 2020 Aug. PMID 32380281
  5. Regulation of zebrafish dorsoventral patterning by phase separation of RNA-binding protein Rbm14. Xiao Y, et al. Cell Discov, 2019. PMID 31636951, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables transcription coregulator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
TATA-binding protein-associated factor 2N
Names
pigpen

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001079973.1 → NP_001073442.1  TATA-binding protein-associated factor 2N

    See identical proteins and their annotated locations for NP_001073442.1

    Status: PROVISIONAL

    Source sequence(s)
    BC128851
    UniProtKB/TrEMBL
    A0A8M1NCI6, A1A5X7
    Related
    ENSDARP00000093187.2, ENSDART00000102410.5
    Conserved Domains (4) summary
    COG0724
    Location:209 → 297
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12535
    Location:209 → 291
    RRM_FUS_TAF15; RNA recognition motif in vertebrate fused in Ewing's sarcoma protein (FUS), TATA-binding protein-associated factor 15 (TAF15) and similar proteins
    sd00029
    Location:342 → 363
    zf-RanBP2; RanBP2-type Zn finger [structural motif]
    pfam00641
    Location:338 → 368
    zf-RanBP; Zn-finger in Ran binding protein and others

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    1825176..1843841 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021481421.2 → XP_021337096.1  TATA-binding protein-associated factor 2N isoform X3

    UniProtKB/TrEMBL
    A0A8M9QLF1
    Conserved Domains (3) summary
    smart00547
    Location:294 → 320
    ZnF_RBZ; Zinc finger domain
    cd12535
    Location:163 → 245
    RRM_FUS_TAF15; RNA recognition motif in vertebrate fused in Ewing's sarcoma protein (FUS), TATA-binding protein-associated factor 15 (TAF15) and similar proteins
    sd00025
    Location:296 → 317
    zf-RanBP2; RanBP2-type Zn finger [structural motif]

  2. XM_005173352.5 → XP_005173409.1  TATA-binding protein-associated factor 2N isoform X1

    UniProtKB/TrEMBL
    A0A8M2BKN1
    Conserved Domains (4) summary
    COG0724
    Location:190 → 278
    RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
    cd12535
    Location:190 → 272
    RRM_FUS_TAF15; RNA recognition motif in vertebrate fused in Ewing's sarcoma protein (FUS), TATA-binding protein-associated factor 15 (TAF15) and similar proteins
    sd00029
    Location:323 → 344
    zf-RanBP2; RanBP2-type Zn finger [structural motif]
    pfam00641
    Location:319 → 349
    zf-RanBP; Zn-finger in Ran binding protein and others

  3. XM_021481420.2 → XP_021337095.1  TATA-binding protein-associated factor 2N isoform X2

    UniProtKB/TrEMBL
    A0A8M9QPV6
    Conserved Domains (3) summary
    smart00547
    Location:313 → 339
    ZnF_RBZ; Zinc finger domain
    cd12535
    Location:182 → 264
    RRM_FUS_TAF15; RNA recognition motif in vertebrate fused in Ewing's sarcoma protein (FUS), TATA-binding protein-associated factor 15 (TAF15) and similar proteins
    sd00025
    Location:315 → 336
    zf-RanBP2; RanBP2-type Zn finger [structural motif]
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials
Tools