yjefn3 YjeF N-terminal domain containing 3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: yjefn3provided by ZNC
Official Full Name: YjeF N-terminal domain containing 3provided by ZNC
Primary source: ZFIN:ZDB-GENE-050208-755
See related: Ensembl:ENSDARG00000061692 AllianceGenome:ZFIN:ZDB-GENE-050208-755
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: apoa1bp2; si:ch211-212d10.3
Summary: Predicted to enable NAD(P)HX epimerase activity. Involved in hematopoietic stem cell proliferation; regulation of Notch signaling pathway; and regulation of cholesterol efflux. Acts upstream of or within membrane raft distribution; negative regulation of angiogenesis; and sprouting angiogenesis. Is expressed in somite. Orthologous to human YJEFN3 (YjeF N-terminal domain containing 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 22

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	22	NC_007133.7 (18389373..18464641)
105	previous assembly	GRCz10 (GCF_000002035.5)	22	NC_007133.6 (18364395..18439663)

Chromosome 22 - NC_007133.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables NAD(P)HX epimerase activity	IBA Inferred from Biological aspect of Ancestor more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in hematopoietic stem cell proliferation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within lipid transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within membrane raft distribution	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within negative regulation of angiogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of Notch signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of cholesterol efflux	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of cholesterol efflux	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within sprouting angiogenesis	IMP Inferred from Mutant Phenotype more info	PubMed

General protein information

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Preferred Names: yjeF N-terminal domain-containing 3

Names: aibp2; apoA-I-binding protein 2; apolipoprotein A-I binding protein like; yjeF N-terminal domain-containing protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001044843.1 → NP_001038308.1 yjeF N-terminal domain-containing 3

Status: PROVISIONAL

Source sequence(s)

BX649279, BX664610

UniProtKB/Swiss-Prot

Q1LVI2

Related

ENSDARP00000082703.3, ENSDART00000088270.4

Conserved Domains (1) summary

cl00318
Location:16 → 246

YjeF_N; YjeF-related protein N-terminus