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prickle1b - prickle homolog 1b

Predicted to enable zinc ion binding activity. Acts upstream of with a positive effect on motor neuron migration. Acts upstream of or within nervous system development and neural crest cell migration. Predicted to be located in membrane. Is expressed in several structures, including mesoderm; myotome; nervous system; neuroepithelial cell; and pharyngeal arch. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 1B. Orthologous to human PRICKLE1 (prickle planar cell polarity protein 1). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa