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npr1b natriuretic peptide receptor 1b [ Danio rerio (zebrafish) ]

Gene ID: 555911, updated on 4-Jan-2025

Summary

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Official Symbol
npr1bprovided by ZNC
Official Full Name
natriuretic peptide receptor 1bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-100805-4
See related
Ensembl:ENSDARG00000018750 AllianceGenome:ZFIN:ZDB-GENE-100805-4
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable ATP binding activity; guanylate cyclase activity; and protein kinase activity. Acts upstream of or within olfactory bulb axon guidance. Predicted to be located in membrane. Is expressed in several structures, including eye; fin; integument; muscle; and renal system. Human ortholog(s) of this gene implicated in myocardial infarction. Orthologous to human NPR1 (natriuretic peptide receptor 1). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See npr1b in Genome Data Viewer
Location:
chromosome: 16
Exon count:
22
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (28903743..28991376)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (28969131..29056750)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene SMAD family member 10b Neighboring gene chromatin target of PRMT1b Neighboring gene gon-4 like b Neighboring gene C-type lectin domain family 4 member A Neighboring gene G patch domain containing 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. The expression of natriuretic peptide receptors in developing zebrafish embryos. Gong J, et al. Gene Expr Patterns, 2018 Sep. PMID 30018004
  2. Attractant and repellent cues cooperate in guiding a subset of olfactory sensory axons to a well-defined protoglomerular target. Taku AA, et al. Development, 2016 Jan 1. PMID 26732841, Free PMC Article
  3. Regulation of cytochrome P450 expression in a novel liver cell line from zebrafish (Brachydanio rerio). Miranda CL, et al. Arch Biochem Biophys, 1993 Sep. PMID 8373170
  4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables guanylate cyclase activity IEA
Inferred from Electronic Annotation
more info
  
enables lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables phosphorus-oxygen lyase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cGMP biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cyclic nucleotide biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within olfactory bulb axon guidance IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within protein phosphorylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
atrial natriuretic peptide receptor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    28903743..28991376
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009292394.4 → XP_009290669.2  atrial natriuretic peptide receptor 1

    UniProtKB/TrEMBL
    A0A8M3AQN2
    Related
    ENSDARP00000010052.8, ENSDART00000018213.9
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials