si:dkey-9i23.15 si:dkey-9i23.15 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: si:dkey-9i23.15provided by ZNC
Official Full Name: si:dkey-9i23.15provided by ZNC
Primary source: ZFIN:ZDB-GENE-090313-361
See related: Ensembl:ENSDARG00000093997 AllianceGenome:ZFIN:ZDB-GENE-090313-361
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to be involved in cellular response to gamma radiation and intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. Predicted to be located in membrane. Orthologous to human TMEM109 (transmembrane protein 109). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: human mouse all
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Genomic context

See si:dkey-9i23.15 in Genome Data Viewer

Location:: chromosome: 1

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (44925422..44928987, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (44224119..44227684, complement)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
involved_in cellular response to gamma radiation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within cellular response to gamma radiation	IEA Inferred from Electronic Annotation more info
involved_in intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: voltage-gated monoatomic cation channel TMEM109

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001145559.1 → NP_001139031.1 voltage-gated monoatomic cation channel TMEM109 precursor

Status: PROVISIONAL

Source sequence(s)

BX901937

UniProtKB/TrEMBL

A0A8N1TTA8, B8A638

Related

ENSDARP00000117097.1, ENSDART00000134635.2

Conserved Domains (1) summary

pfam14965
Location:44 → 216

BRI3BP; Negative regulator of p53/TP53