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synrg synergin, gamma [ Danio rerio (zebrafish) ]

Gene ID: 555257, updated on 9-Dec-2024

Summary

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Official Symbol
synrgprovided by ZNC
Official Full Name
synergin, gammaprovided by ZNC
Primary source
ZFIN:ZDB-GENE-030131-9396
See related
Ensembl:ENSDARG00000073926 AllianceGenome:ZFIN:ZDB-GENE-030131-9396
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
fj67h08; wu:fj67h08
Summary
Predicted to be part of clathrin coat of trans-Golgi network vesicle. Orthologous to human SYNRG (synergin gamma). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
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Genomic context

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See synrg in Genome Data Viewer
Location:
chromosome: 15
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (15886064..15983188, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (15950042..16047173, complement)

Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene transcriptional adaptor 2A Neighboring gene dual specificity phosphatase 14 Neighboring gene uncharacterized LOC137487733 Neighboring gene HNF1 homeobox Ba Neighboring gene dynein, light chain, LC8-type 2a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Dhrs3a regulates retinoic acid biosynthesis through a feedback inhibition mechanism. Feng L, et al. Dev Biol, 2010 Feb 1. PMID 19874812, Free PMC Article
  2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Component Evidence Code Pubs
part_of clathrin coat of trans-Golgi network vesicle IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
synergin gamma

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007126.7 Reference GRCz11 Primary Assembly

    Range
    15886064..15983188 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005157442.5 → XP_005157499.1  synergin gamma isoform X7

    UniProtKB/TrEMBL
    A0A8M2B3J5
    Conserved Domains (4) summary
    cd00052
    Location:206 → 274
    EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
    pfam05819
    Location:892 → 1011
    NolX; NolX protein
    pfam09606
    Location:40 → 341
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cl26386
    Location:233 → 542
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

  2. XM_068213691.1 → XP_068069792.1  synergin gamma isoform X5

  3. XM_068213692.1 → XP_068069793.1  synergin gamma isoform X6

  4. XM_005157441.5 → XP_005157498.1  synergin gamma isoform X4

    UniProtKB/TrEMBL
    A0A8M9Q1R4
    Conserved Domains (4) summary
    cd00052
    Location:306 → 374
    EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
    pfam09606
    Location:40 → 119
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cl25549
    Location:102 → 135
    ARGLU; Arginine and glutamate-rich 1
    cl26386
    Location:333 → 642
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

  5. XM_005157440.5 → XP_005157497.1  synergin gamma isoform X3

    UniProtKB/TrEMBL
    A0A8M9Q5G9
    Related
    ENSDARP00000130488.2, ENSDART00000166583.2
    Conserved Domains (4) summary
    cd00052
    Location:398 → 466
    EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
    pfam09606
    Location:40 → 119
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cl25549
    Location:102 → 135
    ARGLU; Arginine and glutamate-rich 1
    cl26464
    Location:173 → 704
    Atrophin-1; Atrophin-1 family

  6. XM_009291573.4 → XP_009289848.1  synergin gamma isoform X2

    UniProtKB/TrEMBL
    A0A8M3B0W7
    Conserved Domains (4) summary
    cd00052
    Location:398 → 466
    EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
    pfam09606
    Location:40 → 119
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cl25549
    Location:102 → 135
    ARGLU; Arginine and glutamate-rich 1
    cl26464
    Location:173 → 704
    Atrophin-1; Atrophin-1 family

  7. XM_005157439.5 → XP_005157496.1  synergin gamma isoform X1

    UniProtKB/TrEMBL
    A0A8M2B3R6, E7F371
    Related
    ENSDARP00000102639.2, ENSDART00000115129.5
    Conserved Domains (4) summary
    cd00052
    Location:398 → 466
    EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
    pfam09606
    Location:40 → 119
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cl25549
    Location:102 → 135
    ARGLU; Arginine and glutamate-rich 1
    cl26464
    Location:173 → 704
    Atrophin-1; Atrophin-1 family

  8. XM_003200027.6 → XP_003200075.2  synergin gamma isoform X8

    UniProtKB/TrEMBL
    A0A8M9PUQ3
    Conserved Domains (4) summary
    cd00052
    Location:206 → 274
    EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
    pfam05819
    Location:892 → 1011
    NolX; NolX protein
    pfam09606
    Location:40 → 341
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cl26386
    Location:233 → 542
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394941.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    210913..307603 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021472922.2 → XP_021328597.1  synergin gamma isoform X7

    UniProtKB/TrEMBL
    A0A8M2B3J5
    Conserved Domains (4) summary
    cd00052
    Location:206 → 274
    EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
    pfam05819
    Location:892 → 1011
    NolX; NolX protein
    pfam09606
    Location:40 → 341
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cl26386
    Location:233 → 542
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

  2. XM_068218788.1 → XP_068074889.1  synergin gamma isoform X5

  3. XM_021472921.2 → XP_021328596.1  synergin gamma isoform X4

    UniProtKB/TrEMBL
    A0A8M9Q1R4
    Conserved Domains (4) summary
    cd00052
    Location:306 → 374
    EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
    pfam09606
    Location:40 → 119
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cl25549
    Location:102 → 135
    ARGLU; Arginine and glutamate-rich 1
    cl26386
    Location:333 → 642
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

  4. XM_021472920.2 → XP_021328595.1  synergin gamma isoform X3

    UniProtKB/TrEMBL
    A0A8M9Q5G9
    Conserved Domains (4) summary
    cd00052
    Location:398 → 466
    EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
    pfam09606
    Location:40 → 119
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cl25549
    Location:102 → 135
    ARGLU; Arginine and glutamate-rich 1
    cl26464
    Location:173 → 704
    Atrophin-1; Atrophin-1 family

  5. XM_021472918.2 → XP_021328593.1  synergin gamma isoform X1

    UniProtKB/TrEMBL
    A0A8M2B3R6, E7F371
    Conserved Domains (4) summary
    cd00052
    Location:398 → 466
    EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
    pfam09606
    Location:40 → 119
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cl25549
    Location:102 → 135
    ARGLU; Arginine and glutamate-rich 1
    cl26464
    Location:173 → 704
    Atrophin-1; Atrophin-1 family

  6. XM_021472924.2 → XP_021328599.1  synergin gamma isoform X8

    UniProtKB/TrEMBL
    A0A8M9PUQ3
    Conserved Domains (4) summary
    cd00052
    Location:206 → 274
    EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
    pfam05819
    Location:892 → 1011
    NolX; NolX protein
    pfam09606
    Location:40 → 341
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cl26386
    Location:233 → 542
    DNA_pol3_gamma3; DNA polymerase III subunits gamma and tau domain III

  7. XM_021472919.2 → XP_021328594.1  synergin gamma isoform X2

    UniProtKB/TrEMBL
    A0A8M3B0W7
    Conserved Domains (4) summary
    cd00052
    Location:398 → 466
    EH; Eps15 homology domain; found in proteins implicated in endocytosis, vesicle transport, and signal transduction. The alignment contains a pair of EF-hand motifs, typically one of them is canonical and binds to Ca2+, while the other may not bind to Ca2+. A ...
    pfam09606
    Location:40 → 119
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cl25549
    Location:102 → 135
    ARGLU; Arginine and glutamate-rich 1
    cl26464
    Location:173 → 704
    Atrophin-1; Atrophin-1 family

  8. XM_068218787.1 → XP_068074888.1  synergin gamma isoform X9

Nucleotide Protein
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