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spra - sepiapterin reductase a

Predicted to enable sepiapterin reductase (NADP+) activity. Predicted to be involved in tetrahydrobiopterin biosynthetic process. Predicted to be located in cytoplasm. Is expressed in diencephalon; melanocyte; midbrain hindbrain boundary; and presumptive neural retina. Human ortholog(s) of this gene implicated in dystonia and sepiapterin reductase deficiency. Orthologous to human SPR (sepiapterin reductase). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa