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ugt2a2 UDP glucuronosyltransferase 2 family, polypeptide A2 [ Danio rerio (zebrafish) ]

Gene ID: 553952, updated on 9-Dec-2024

Summary

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Official Symbol
ugt2a2provided by ZNC
Official Full Name
UDP glucuronosyltransferase 2 family, polypeptide A2provided by ZNC
Primary source
ZFIN:ZDB-GENE-080721-21
See related
Ensembl:ENSDARG00000051940 AllianceGenome:ZFIN:ZDB-GENE-080721-21
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:112490; zgc:112491
Summary
Is expressed in liver; muscle; and pleuroperitoneal region. Orthologous to several human genes including UGT2B10 (UDP glucuronosyltransferase family 2 member B10); UGT2B11 (UDP glucuronosyltransferase family 2 member B11); and UGT2B15 (UDP glucuronosyltransferase family 2 member B15). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See ugt2a2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (69926766..69944092, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (69154214..69171540, complement)

Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene YTH N6-methyladenosine RNA binding protein C1 Neighboring gene fukutin Neighboring gene UDP glucuronosyltransferase 2 family, polypeptide A4 Neighboring gene UDP glucuronosyltransferase 2 family, polypeptide A3 Neighboring gene UDP glucuronosyltransferase 2 family, polypeptide A1 Neighboring gene DnaJ (Hsp40) homolog, subfamily C , member 25 Neighboring gene regulator of G protein signaling 3a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Adaptive evolution of multiple-variable exons and structural diversity of drug-metabolizing enzymes. Li C, et al. BMC Evol Biol, 2007 May 2. PMID 17475008, Free PMC Article
  2. Characterization of the zebrafish Ugt repertoire reveals a new class of drug-metabolizing UDP glucuronosyltransferases. Wang Y, et al. Mol Pharmacol, 2014 Jul. PMID 24728488
  3. Cloning and comparative analyses of the zebrafish Ugt repertoire reveal its evolutionary diversity. Huang H, et al. PLoS One, 2010 Feb 10. PMID 20161780, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Clone Names

  • MGC112490

General protein information

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Preferred Names
UDP-glucuronosyltransferase 2A2
NP_001018306.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001020470.2 → NP_001018306.2  UDP-glucuronosyltransferase 2A2 precursor

    Status: VALIDATED

    Source sequence(s)
    CR753888, CU571335
    UniProtKB/TrEMBL
    A0A8M1N5N2, B8JMA7
    Related
    ENSDARP00000109851.2, ENSDART00000127782.4
    Conserved Domains (2) summary
    PHA03392
    Location:256 → 487
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    pfam00201
    Location:23 → 521
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007116.7 Reference GRCz11 Primary Assembly

    Range
    69926766..69944092 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395248.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    212110..228683 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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