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dhrs7cb dehydrogenase/reductase (SDR family) member 7Cb [ Danio rerio (zebrafish) ]

Gene ID: 553684, updated on 9-Dec-2024

Summary

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Official Symbol
dhrs7cbprovided by ZNC
Official Full Name
dehydrogenase/reductase (SDR family) member 7Cbprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050522-226
See related
Ensembl:ENSDARG00000071877 AllianceGenome:ZFIN:ZDB-GENE-050522-226
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
dhrs7c; zgc:112176
Summary
Predicted to enable oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Predicted to be involved in intracellular calcium ion homeostasis. Predicted to be located in extracellular region and membrane. Orthologous to human DHRS7C (dehydrogenase/reductase 7C). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
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Genomic context

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See dhrs7cb in Genome Data Viewer
Location:
chromosome: 12
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (455552..463995, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (449611..458054, complement)

Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene gsg1-like 2b Neighboring gene heparan sulfate (glucosamine) 3-O-sulfotransferase 3-like Neighboring gene myosin phosphatase Rho interacting protein Neighboring gene si:dkey-94l16.4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Combined effects of polystyrene microplastics and natural organic matter on the accumulation and toxicity of copper in zebrafish. Qiao R, et al. Sci Total Environ, 2019 Sep 10. PMID 31117014
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC112176

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on CH-OH group of donors IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in intracellular calcium ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
dehydrogenase/reductase (SDR family) member 7Cb
Names
dehydrogenase/reductase (SDR family) member 7C

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001020657.1 → NP_001018493.1  dehydrogenase/reductase (SDR family) member 7Cb

    See identical proteins and their annotated locations for NP_001018493.1

    Status: PROVISIONAL

    Source sequence(s)
    BC095682
    UniProtKB/Swiss-Prot
    A8E5C5, Q502I7
    UniProtKB/TrEMBL
    A0A8M9Q8F6
    Related
    ENSDARP00000097447.4, ENSDART00000106669.5
    Conserved Domains (2) summary
    cd05332
    Location:35 → 309
    11beta-HSD1_like_SDR_c; 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1)-like, classical (c) SDRs
    pfam00106
    Location:38 → 219
    adh_short; short chain dehydrogenase

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007123.7 Reference GRCz11 Primary Assembly

    Range
    455552..463995 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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