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os9 OS9 endoplasmic reticulum lectin [ Danio rerio (zebrafish) ]

Gene ID: 553455, updated on 9-Dec-2024

Summary

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Official Symbol
os9provided by ZNC
Official Full Name
OS9 endoplasmic reticulum lectinprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060929-32
See related
Ensembl:ENSDARG00000020301 AllianceGenome:ZFIN:ZDB-GENE-060929-32
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:153838
Summary
Predicted to enable carbohydrate binding activity. Predicted to be involved in retrograde protein transport, ER to cytosol. Predicted to act upstream of or within ERAD pathway. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum lumen. Orthologous to human OS9 (OS9 endoplasmic reticulum lectin). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
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Genomic context

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See os9 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (39202685..39218590, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (39203994..39221048, complement)

Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene tachykinin precursor 3b Neighboring gene core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, like b Neighboring gene beta-1,4-N-acetyl-galactosaminyl transferase 1b Neighboring gene Rho guanine nucleotide exchange factor (GEF) 25b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. OS-9 regulates the transit and polyubiquitination of TRPV4 in the endoplasmic reticulum. Wang Y, et al. J Biol Chem, 2007 Dec 14. PMID 17932042
  2. Many genes in fish have species-specific asymmetric rates of molecular evolution. Steinke D, et al. BMC Genomics, 2006 Feb 8. PMID 16466575, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC153838

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables carbohydrate binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within ERAD pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within endoplasmic reticulum unfolded protein response IEA
Inferred from Electronic Annotation
more info
  
involved_in endoplasmic reticulum unfolded protein response IEA
Inferred from Electronic Annotation
more info
  
involved_in retrograde protein transport, ER to cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
is_active_in endoplasmic reticulum lumen IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein OS-9
Names
amplified in osteosarcoma
osteosarcoma amplified 9, endoplasmic reticulum lectin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001075108.1 → NP_001068576.1  protein OS-9

    See identical proteins and their annotated locations for NP_001068576.1

    Status: PROVISIONAL

    Source sequence(s)
    BC124472
    UniProtKB/TrEMBL
    Q08C06
    Related
    ENSDARP00000120218.1, ENSDART00000133305.3
    Conserved Domains (2) summary
    pfam07915
    Location:72 → 143
    PRKCSH; Glucosidase II beta subunit-like protein
    cl06793
    Location:137 → 195
    PRKCSH; Glucosidase II beta subunit-like protein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007117.7 Reference GRCz11 Primary Assembly

    Range
    39202685..39218590 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005166042.5 → XP_005166099.1  protein OS-9 isoform X1

    UniProtKB/TrEMBL
    A0A8M2BDH0
    Related
    ENSDART00000041882.9
    Conserved Domains (2) summary
    pfam07915
    Location:106 → 177
    PRKCSH; Glucosidase II beta subunit-like protein
    cl06793
    Location:171 → 229
    PRKCSH; Glucosidase II beta subunit-like protein

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394661.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    76463..92343 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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