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kdm5c - lysine demethylase 5C

Predicted to enable histone H3K4me/H3K4me2/H3K4me3 demethylase activity. Acts upstream of or within negative regulation of neuron apoptotic process. Predicted to be located in chromatin. Predicted to be active in nucleus. Is expressed in brain; head; muscle; spinal cord; and telencephalon. Human ortholog(s) of this gene implicated in descending colon cancer and syndromic X-linked intellectual disability Claes-Jensen type. Orthologous to several human genes including KDM5C (lysine demethylase 5C). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa